陕西省渭南市高致病性禽流感免疫抗体监测与分析  

Monitoring and Analysis of Antibodies against Highly Pathogenic Avian Influenza in Weinan City,Shaanxi Province

作　　者：南苹瑶 徐梦迪 秦鸽鸽 白鸽 王国超 马宁君 吴奇强 Nan Pingyao;Xu Mengdi;Qin Gege;Bai Ge;Wang Guochao;Ma Ningjun;Wu Qiqiang(Weinan Center for Animal Disease Prevention and Control,Weinan 714000,Shaanxi,China)

机构地区：[1]渭南市动物疫病预防控制中心,陕西渭南714000

出　　处：《中国动物检疫》2024年第1期16-19,共4页China Animal Health Inspection

基　　金：渭南市高层次人才“特支计划”项目(20200039,20210086)。

摘　　要：为了解渭南市H5亚型和H7亚型高致病性禽流感(HPAI)免疫情况,2020—2022年,随机抽取规模养鸡场和散养户采集血清样品,采用血凝和血凝抑制试验进行禽流感病毒免疫抗体检测,并对检测数据进行统计分析。结果显示:H5亚型HPAI免疫抗体合格率为96.28%,H7亚型HPAI为92.24%;2020年H5亚型HPAI抗体合格率极显著高于H7亚型(P<0.001),2022年H5亚型HPAI抗体合格率显著高于H7亚型(P<0.05);12个区域的H5亚型HPAI抗体合格率为85.00%~100%,H7亚型HPAI抗体合格率为70.48%~98.80%;规模养鸡场、散养户的H5亚型、H7亚型HPAI平均抗体合格率均存在显著性差异(P<0.05)。结果表明,渭南市H5亚型和H7亚型HPAI抗体水平较高,免疫效果较好。建议规模化养鸡场持续做好免疫效果评估,散养户加强免疫主体责任意识,以进一步提升禽流感整体防控水平。In order to investigate the immunization status of H5 and H7 subtype highly pathogenic avian influenza(HPAI)in Weinan City,serum samples were randomly selected from intensive chicken farms and free-range households from 2020 to 2022 to detect antibodies against avian influenza virus using hemagglutination(HA)and hemagglutination inhibition(HI)tests,then test data were statistically analyzed.The results showed that the qualification rate of antibodies against H5 subtype HPAI virus was 96.28%,and that of H7 subtype HPAI virus was 92.24%;the former was significant higher than the latter in 2020(P<0.001)and 2022(P<0.05).The qualification rates of antibodies against H5 subtype HPAI virus were from 85.00%to 100%in 12 regions,and those of H7 subtype HPAI virus ranged from 70.48%to 98.80%;the average antibody qualification rates of the two subtypes were significantly different(P<0.05)in intensive farms and free-range households.In conclusion,the antibody levels of the two subtypes of HPAI were relatively high in Weinan City where the immune effect was good.It was thus recommended that intensive farms should further evaluate the immune effect,and free-range households should improve their awareness of responsibilities as actors to improve the general level of avian influenza prevention and control.

关 键 词：高致病性禽流感 抗体合格率 H5亚型 H7亚型 

分 类 号：S851.3[农业科学—预防兽医学]