高效氯氰菊酯和吡丙醚在芥蓝中的残留消解及膳食暴露风险评估  

Dissipation,residue and dietary risk assessment of beta-cypermethrin-pyriproxyfen in Chinese kale

作　　者：唐红霞[1] 李玉博[1] 张颂函 吴竞 董茂锋[1] 王伟民[1] 赵莉[2] TANG Hongxia;LI Yubo;ZHANG Songhan;WU Jing;DONG Maofeng;WANG Weimin;ZHAO Li(Pesticide Safety Evaluation Research Center,Key Laboratory for Safety Assessment(Environment)of Agricultural Genetically Modified Organisms,Ministry of Agriculture and Rural Affairs,Shanghai Academy of Agricultural Sciences,Shanghai 201106,China;Shanghai Agricultural Technical Extension Service Center,Shanghai 201103,China)

机构地区：[1]上海市农业科学院农药安全评价研究中心,农业农村部转基因生物安全评价(环境)重点实验室,上海201106 [2]上海市农业技术推广服务中心,上海201103

出　　处：《植物保护》2024年第1期232-238,271,共8页Plant Protection

基　　金：上海市科技兴农技术推广项目(沪农科推字(2022)第2-4号)。

摘　　要：为明确高效氯氰菊酯和吡丙醚在芥蓝上施用后的残留行为和膳食暴露风险,研究基于规范田间残留试验、目标农药在芥蓝上残留分析方法,得到芥蓝中2种农药的残留水平,结合我国膳食结构不同性别/年龄组食物消费量及体重数据评估了高效氯氰菊酯和吡丙醚对各类消费人群的长期和短期膳食摄入风险。结果表明:高效氯氰菊酯和吡丙醚分别在0.01~1.0 mg/L和0.005~1.0 mg/L范围内线性关系良好,决定系数(R2)≥0.996 7。在3个添加水平下,芥蓝中2种农药的平均回收率为70.6%~113.4%,相对标准偏差(RSD)为0.5%~8.5%,定量限均为0.01 mg/kg。10%高氯·吡丙醚微乳剂以推荐高剂量施药,高效氯氰菊酯和吡丙醚在芥蓝中的消解符合一级动力学,半衰期分别为3.9~10.1 d和4.8~6.3 d。最终残留试验结果表明,最后一次施药3、5、7、10 d后,芥蓝中高效氯氰菊酯的最终残留量≤0.904 mg/kg,吡丙醚的最终残留量≤0.202 mg/kg。膳食风险评估表明,我国不同人群的长期慢性暴露风险最大值为27.26%;短期急性暴露风险最大值为67.17%,表明对不同年龄段、不同性别人群健康不会产生不可接受的风险。The study aimed to confirm the residue dissipation and the dietary risk of beta-cypermethrin and pyriproxyfen in Chinese kale.Based on good agricultural practices and analytical methods,residue levels of beta-cypermethrin and pyriproxyfen were determined in Chinese kale.Long-term and short-term dietary intake risk assessment of beta-cypermethrin and pyriproxyfen were evaluated based on the date of food consumption and weight data of different gender/age groups in dietary structure studies.Good linear relationships were presented in the range of 0.01-1.0 mg/L and 0.005-1.0 mg/L,respectively,and the coefficient of determination(R^(2))were above 0.9967.The average recoveries of the pesticides in the Chinese kale with three spiked levels varied from 70.6%to 113.4%,with relative standard deviations(RSDs)of 0.5%-8.5%.The limit of qualification(LOQ)was 0.01 mg/kg.Residue experiments of beta-cypermethrin•pyriproxyfen 10%microemulsion(ME)in Chinese kale were carried out with each high recommended dosage.The dissipations of beta-cypermethrin and pyriproxyfen were followed first-order kinetic equations.The degradation half-lives were 3.9-10.1 days and 4.8-6.3 days,respectively.The final residues of beta-cypermethrin and pyriproxyfen in Chinese kale were lower than 0.094 mg/kg and 0.202 mg/kg,respectively,after 3,5,7,10 days of the last application.For dietary exposure risk assessments,the maximum value of the risk of chronic exposure under different Chinese ages was 27.26%and the maximum value of the risk of acute exposure was 67.17%,and both below 100%.It indicated that the agents of beta-cypermethrin•pyriproxyfen 10%ME sprayed on Chinese kale at the recommended dosages had no unacceptable potential risks for Chinese consumers.

关 键 词：芥蓝 高效氯氰菊酯 吡丙醚 膳食摄入评估 

分 类 号：S481.8[农业科学—农药学]