毒品依赖综合征患者罹患高血压的临床特征分析  

Analysis of clinical characteristics of hypertension in methamphetamine and heroin addicts

作　　者：禹杭远 张利 张英霞 周艳 YU Hangyuan;ZHANG Li;ZHANG Yingxia;ZHOU Yan(Li Kang Compulsory Isolation Drug Rehabilitation Center of Beijing,Beijing 102600,China)

机构地区：[1]北京市利康教育矫治所,北京102600

出　　处：《医药前沿》2023年第35期20-23,共4页Journal of Frontiers of Medicine

摘　　要：目的:分析毒品依赖综合征患者的临床特征,探究不同类型毒品依赖者高血压患病情况的差异,为临床早期预防及诊疗提供依据。方法:选取2019年1月—2023年5月因使用甲基苯丙胺或海洛因被强制在北京市利康教育矫治所进行隔离戒毒的患者,完成入组患者的常规体检及健康调查,按照是否患有高血压分为高血压组和非高血压组。入院后收集患者一般资料,包括年龄、性别、吸烟史、饮酒史、家族史等,对比分析两组间的临床特征差异。采用倾向性评分匹配(PSM)消除对高血压发病有重要影响的因素在组间分布的不均衡,对甲基苯丙胺依赖者及甲基苯丙胺与海洛因共同依赖者进行相关变量的匹配,匹配比例为2:1,分析匹配后两者间高血压的发病率差异。结果:178例毒品依赖综合征患者,患有高血压57例,设为高血压组;未患高血压121例,设为非高血压组。高血压组患者年龄、有吸烟史与高血压家族史、吸食海洛因以及甲基苯丙胺与海洛因混吸的占比均大于非高血压组,差异有统计学意义(P<0.05),而高血压组与非高血压组性别、身体质量指数(BMI)、饮酒史比较,差异无统计学意义(P>0.05)。剔除无法匹配者,最终获得甲基苯丙胺组72例,甲基苯丙胺与海洛因混吸组36例。混吸组高血压患者占比大于甲基苯丙胺组,差异有统计学意义(P<0.05),而甲基苯丙胺组与混吸组的一般资料(包括性别、年龄、BMI、吸烟史、饮酒史、高血压家族史)比较,差异均无统计学意义(P>0.05)。结论:罹患高血压的毒品依赖综合征患者年龄相对较大,有吸烟史与高血压家族史的占比相对较高;甲基苯丙胺与海洛因混吸者较单纯吸食甲基苯丙胺更易罹患高血压。Objective To analyze the clinical characteristics associated with hypertension in drug addicts under compulsory rehabilitation,and explore the differences in the prevalence of hypertension among different types of drug addictive,so as to provide evidence for early clinical prevention and diagnosis.Methods Patients addicted with methamphetamine or heroin who were under compulsory isolation in our hospital from January 2019 to May 2023 were enrolled,and they were divided into hypertension group and control group.We completed routine physical examination and health survey of patients,then collected general data,including sex,age,smoking,drinking,and family history of hypertension.We analyzed the general data between the two groups.The propensity score matching(PSM)was used to match the clinical characteristics of the addicted of methamphetamine and the co-addicted of methamphetamine and heroin,the matching ratio was 2:1,and the incidence of hypertension between the two groups was compared.Results Of the 178 patients with drug dependence syndrome,57 suffered from hypertension and were set up as the hypertensive group,and 121 did not suffer from hypertension and were set up as the non-hypertensive group.The age of patients in the hypertensive group,the percentage of patients with smoking history and family history of hypertension,and the percentage of heroin and methamphetamine and heroin mixing were greater than those in the non-hypertensive group,and the difference was statistically significant(P<0.05),whereas the comparison of gender,BMI,and history of alcohol consumption between the hypertensive group and the non-hypertensive group did not have any statistically significant difference(P>0.05).Those who could not be matched were excluded,resulting in 72 cases in the methamphetamine group and 36 cases in the mixed methamphetamine and heroin group.The proportion of hypertensive patients in the mixed-smoking group was greater than that in the methamphetamine group,and the difference was statistically significant(P<0.0

关 键 词：甲基苯丙胺 海洛因 毒品 依赖综合征 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]