婴幼儿哮喘遗传及特应性体质影响因素研究进展  

Research progress on influencing factors of heredity and atopic constitution of infantile asthma

作　　者：严秋丽 钮文思 陈颖青 YAN Qiuli;NIU Wensi;CHEN Yingqing(Department of Digestive Infection,Suzhou Wujiang District Children’s Hospital,Jiangsu,Suzhou 215200,China)

机构地区：[1]江苏省苏州市吴江区儿童医院消化感染科,江苏苏州215200

出　　处：《中国医药科学》2023年第24期39-41,共3页China Medicine And Pharmacy

基　　金：苏州市医学重点扶持学科(SZFCXK202134);2020年度苏州市吴江区儿童医院青年研究基金项目(2020QN01)。

摘　　要：支气管哮喘简称“哮喘”,其特征为反复发作的喘息、气促、胸闷或咳嗽,常在夜间和/或清晨发作,严重时会出现呼吸困难及呼吸衰竭。婴幼儿哮喘是儿科常见的呼吸系统疾病,喘息反复发作影响患儿身心健康,给家庭及社会造成经济负担,哮喘已成为全球关注的公共卫生问题。目前,国内外多项研究表明,哮喘发生与遗传密切相关,因此有必要对儿童哮喘进行系统研究和探讨相关危险因素分析,本文主要对哮喘相关基因及特应性体质进行分析,早期识别哮喘患儿,为临床预防提供依据。Bronchial asthma is called asthma for short,characterized by recurrent wheezing,shortness of breath,chest tightness or cough,which often occurs at night and/or early morning,and in severe cases,dyspnea and respiratory failure may occur.Infantile asthma is a common respiratory disease in pediatrics.Recurrent wheezing affects physical and mental health of children and causes economic burden to families and society.Asthma has become a public health problem of global concern.At present,many studies at home and abroad show that the occurrence of asthma is closely related to heredity,so it is necessary to systematically study asthma in children and discuss the analysis of related risk factors.This paper mainly analyzes asthmarelated genes and atopic constitution,so as to identify children with asthma early and provide basis for clinical prevention.

关 键 词：婴幼儿 哮喘 基因 特应性体质 

分 类 号：R725.6[医药卫生—儿科]