低温透析模式预防透析中低血压的效果Meta分析  

Meta-analysis of the effect of cold dialysis mode on preventing intradialytic hypotension

作　　者：杨洁 王红叶 张蕊[1] Yang Jie;Wang Hongye;Zhang Rui(Department of Nephrology,Second Hospital Affiliated to Harbin Medical University,Harbin 150001,Heilongjiang Province,China)

机构地区：[1]哈尔滨医科大学附属第二医院肾内科,黑龙江150001

出　　处：《中华肾病研究电子杂志》2023年第6期314-322,共9页Chinese Journal of Kidney Disease Investigation（Electronic Edition）

摘　　要：目的分析低温透析模式预防透析中低血压的效果。方法检索PubMed、Embase、Cochrane Library、Web of Science、中国知网等数据库,根据纳入及排除标准进行文献筛选、质量评定和数据提取,采用RevMan 5.3软件进行Meta分析。结果共纳入38篇研究,涉及994例患者,共计9653例次透析。Meta分析结果显示,低温透析模式可在不降低透析充分性的前提下(MD=0.02,95%CI:-0.02~0.05,P=0.43),降低透析中低血压的发生风险(RR=0.50,95%CI:0.42~0.59,P<0.001),提高透析后收缩压(MD=11.26,95%CI:7.45~15.08,P<0.001)和透析后舒张压(MD=3.08,95%CI:0.78~5.38,P=0.009)。结论低温透析模式可降低透析中低血压的发生风险,提高透析后血压,且不降低透析充分性。Objective To analyze the effect of cold dialysis mode in preventing intradialytic hypotension.Methods The databases were retrieved including PubMed,Embase,Cochrane Library,Web of Science,and China National Knowledge Infrastructure(CNKI),etc.Based on inclusion and exclusion criteria,the literatures received screening,quality evaluation,and data extraction.RevMan 5.3 software was used for meta-analysis.Results A total of 38 studies were included,involving 994 patients and a total of 9653 dialysis sessions.The results of meta-analysis showed that cold dialysis mode reduced the risk of intradialytic hypotension(RR=0.50,95%CI:0.42-0.59,P<0.001)without reducing the adequacy of dialysis(MD=0.02,95%CI:-0.02-0.05,P=0.43).The cold dialysis mode increased both the postdialysis systolic blood pressure(MD=11.26,95%CI:7.45-15.08,P<0.001)and the postdialysis diastolic blood pressure(MD=3.08,95%CI:0.78-5.38,P=0.009).Conclusion Cold dialysis could lower the risk of intradialytic hypotension,increase the postdialysis blood pressure without reducing the dialysis adequacy.

关 键 词：低温透析 透析中低血压 透析充分性 META分析 

分 类 号：R692[医药卫生—泌尿科学]