下肢气压泵联合低分子肝素在高危静脉血栓孕产妇剖宫产术后中的应用  

Application of lower extremity pressure pump apparatus combined with low-molecular weight heparin in pregnant women with high-risk venous thrombosis after cesarean section

作　　者：许丽雯 李婉萍 王晨 王晓莹 XU Liwen;LI Wanping;WANG Chen;WANG Xiaoying(Department of Obstetrics,Dalian Women and Children Medical Center(Group),Dalian,Liaoning,116000,China)

机构地区：[1]大连市妇女儿童医疗中心(集团)产科,辽宁大连116000

出　　处：《当代医学》2023年第33期5-8,共4页Contemporary Medicine

摘　　要：目的探讨气压治疗仪联合低分子肝素在高危静脉血栓孕产妇剖宫产术后中的应用价值。方法选取2019年11月至2021年6月于大连市妇女儿童医疗中心(集团)行剖宫产术的96例静脉血栓高危孕妇作为研究对象,采用随机数字表法分为观察组与对照组,每组48例。对照组应用低分子肝素治疗,观察组应用下肢气压泵联合低分子肝素治疗,比较两组高危因素、手术前后凝血功能指标[纤维蛋白原(FIB)水平、凝血酶时间(TT)、部分凝血酶原时间(APTT)、凝血酶原时间(PT)]、手术前后血液流变学指标[全血高切黏度(HBV)、血浆黏度(PV)、血细胞沉降率(ESR)、全血低切黏度(LBV)]及并发症发生情况。结果两组体重指数(BMI)及妊娠高血压综合征、心脏病、糖尿病、抗凝脂抗体阳性占比比较差异无统计学意义。术后,两组TT均长于术前,FIB水平均低于术前,观察组APTT、PT均长于术前,且观察组APTT、TT、PT均长于对照组,FIB水平低于对照组,差异有统计学意义(P<0.05)。对照组APTT、PT手术前后比较差异无统计学意义。术后,两组HBV、LBV、ESR均低于术前,观察组PV低于术前,且观察组HBV、PV、LBV、ESR均低于对照组,差异有统计学意义(P<0.05)。对照组手术前后PV比较差异无统计学意义。两组并发症发生率比较差异无统计学意义。结论下肢气压泵联合低分子肝素治疗剖宫产术后静脉血栓高危孕妇疗效确切,可明显改善患者血液凝固障碍、血液变形性与流动性,有效缓解其临床症状,值得临床推广应用。Objective To investigate the application value of barometric pneumatic therapeutic apparatus combined with low-molecular weight heparin in pregnant women with high-risk venous thrombosis after cesarean section.Methods 96 pregnant women with high risk of venous thrombosis who underwent cesarean section in Dalian Women and Children Medical Center(Group)from November 2019 to June 2021 were selected as the study subjects,and they were divided into the observation group and the control group according to random number table method,with 48 cases in each group.The control group was treated with low-molecular weight heparin,the observation group was treated with lower extremity pressure pump combined with low-molecular weight heparin.The risk factors,coagulation function indexes(fibrinogen[FIB]level,thrombin time[TT],partial prothrombin time[APTT],prothrombin time[PT]),hemorheology indexes(whole blood high shear viscosity[HBV],plasma viscosity[PV],hemocyto sedimentation rate[ESR],whole blood low shear viscosity[LBV])before and after operation and the incidence of complications were compared between the two groups.Results There were no significant differences in body mass index(BMI),the proportion of gestational hypertension syndrome,heart disease,diabetes,anticoagulant antibody positive between the two groups.After treatment,TT of the two groups were longer than before operation,the levels of FIB were lower than before operation,APTT and PT in the observation group were longer than before operation,APTT,TT and PT in the observation group were longer than the control group,level of FIB was lower than the control group,the differences were statistically significant(P<0.05).There was no significant difference in APTT and PT before and after operation in the control group.After operation,HBV,LBV and ESR of the two groups were lower than before operation,PV in observation group was lower than before operation,and HBV,PV,LBV and ESR in the observation group were lower than those the control group,the differences were statistic

关 键 词：静脉血栓 剖宫产术 下肢气压泵 低分子肝素 

分 类 号：R719.8[医药卫生—妇产科学]