2型糖尿病及糖尿病前期患者心率变异性分析  

Analysis of heart rate variability in patients with type 2 diabetes and pre-diabetes

作　　者：尹冰 黄艺 王毅芳 YIN Bing;HUANG Yi;WANG Yifang(Department of Cardiac Electrophysiology,South Campus of Xiangtan Central Hospital,Xiangtan Hunan 411101,China)

机构地区：[1]湘潭市中心医院南院区心电生理科,湖南湘潭411101

出　　处：《实用心电学杂志》2024年第1期49-52,共4页Journal of Practical Electrocardiology

摘　　要：目的探讨2型糖尿病及糖尿病前期患者心率变异性(heart rate variability,HRV)的变化情况。方法选取2型糖尿病确诊患者58例(糖尿病组)和糖尿病前期患者40例(糖尿病前期组),再选取61例健康体检者(对照组)。将糖尿病组、糖尿病前期组的各项HRV指标与对照组进行对比。结果糖尿病组SDNN、SDANN、rMSSD、PNN50、HF、LF、LF/HF值分别为(96.27±16.32)ms、(86.40±15.66)ms、(25.47±4.02)ms、(4.47±1.18)%、127.86±30.30、242.03±65.39、1.99±0.16;糖尿病前期组上述HRV指标值分别为(100.90±13.28)ms、(91.88±12.20)ms、(26.23±3.68)ms、(4.61±0.87)%、133.90±19.15、265.68±39.64、1.94±0.16。糖尿病及糖尿病前期患者的SDNN、SDANN、rMSSD、PNN50、LF、HF等均较健康人群有不同程度的下降(P均<0.05),LF/HF无明显改变。结论不仅在2型糖尿病患者中,在糖尿病前期人群中就已出现HRV改变。早期监测HRV指标有利于早期发现和诊断心血管自主神经病变。Objective To explore the changes of heart rate variability(HRV)in patients with type 2 diabetes and pre-diabetes.Methods We selected 58 patients diagnosed with type 2 diabetes(diabetes group),40 patients with pre-diabetes(pre-diabetes group),and 61 healthy physical examinees(control group).Each HRV index of the diabetes and pre-diabetes groups was compared with that of the control group.Results The values of SDNN,SDANN,rMSSD,PNN50,HF,LF and LF/HF in the diabetes group were separately(96.27±16.32)ms,(86.40±15.66)ms,(25.47±4.02)ms,(4.47±1.18)%,127.86±30.30,242.03±65.39 and 1.99±0.16;the values of the above HRV indexes in the pre-diabetes group were separately(100.90±13.28)ms,(91.88±12.20)ms,(26.23±3.68)ms,(4.61±0.87)%,133.90±19.15,265.68±39.64 and 1.94±0.16.In the patients with diabetes and pre-diabetes,SDNN,SDANN,rMSSD,PNN50,LF and HF all decreased to varying degrees compared with healthy people(P<0.05)while there was no significant change in LF/HF.Conclusion HRV changes occur not only in type 2 diabetes but also in the population with pre-diabetes.Early monitoring of HRV indexes helps to make early detection and diagnosis of cardiovascular autonomic neuropathy.

关 键 词：2型糖尿病 糖尿病前期 心率变异性 心血管自主神经病变 

分 类 号：R587.1[医药卫生—内分泌]