运动干预对改善认知衰弱老年人身体和认知功能的系统评价和Meta分析  

Effect of the exercise intervention on improving physical and cognitive functions in elderly people with cognitive decline:a systematic review and Meta-analysis

作　　者：童新梅 钟名阳 杨春晓 朱丹 郑丹萍 农秀明[2] TONG Xinmei;ZHONG Mingyang;YANG Chunxiao;ZHU Dan;ZHENG Danping;NONG Xiuming(Guangxi University of Traditional Chinese Medicine,Guangxi 530000,China)

机构地区：[1]广西中医药大学,530000 [2]广西中医药大学第一附属医院,530000

出　　处：《全科护理》2024年第3期420-425,共6页Chinese General Practice Nursing

摘　　要：目的:系统评价运动干预在改善认知衰弱老年人身体和认知功能的有效性。方法:计算机检索PubMed、Embase、中国知网等国内外数据库,检索时限从建库至2023年3月30日。纳入老年认知衰弱病人使用运动干预的随机对照研究。由2名研究者独立进行文献筛选、资料提取、质量评价后,采用RevMan 5.3软件进行分析。结果:共纳入13篇文献,2490例病人,Meta分析结果显示,运动干预有助于改善衰弱水平:埃德蒙顿衰弱量表(EFS)评分[MD=-0.97,95%CI(-1.30,-0.64),P<0.01];身体活动能力:起立-行走计时试验(TUG)测试[MD=-1.07,95%CI(-1.36,-0.78),P<0.01];认知功能:蒙特利尔认知评估量表(MoCA)评分[MD=3.78,95%CI(3.09,4.47),P<0.01]、额叶功能评定量表(FAB)评分[MD=1.47,95%Cl(0.33,2.62),P=0.01]。结论:运动干预可以改善认知衰弱老年人身体和认知功能,但目前关于不同运动强度对认知衰弱老年人的益处仍有争议,缺乏固定最佳运动强度的证据。Objective:To systematically evaluate the effect of exercise intervention in improving physical and cognitive functions in elderly people with cognitive decline.Methods:Randomized controlled trials(RCTs)of exercise intervention in elderly patients with cognitive decline were retrieved from databases in abroad and at home,such as PubMed,Embase,and China National Knowledge Infrastructure(CNKI),from the establishment of the database to March 2023.After 2 researchers independently conducted literature screening,data extraction and quality assessment,RevMan 5.3 software was used for analysis.Results:A total of 13 articles involving 2490 patients were included.Meta-analysis results showed that exercise intervention can help improve the level of frailty:EFS score[MD=-0.97,95%CI(-1.30,-0.64,P<0.01)],TUG test in physical activity[MD=-1.07,95%CI(-1.36,-0.78),P<0.01],MoCA score in cognitive function[MD=3.78,95%CI(3.09,4.47,P<0.01)],and FAB score[MD=1.47,95%Cl(0.33,2.62,P=0.01)].Conclusions:Exercise intervention can improve the physical and cognitive functions of elderly people with cognitive decline.However,there is still controversy about the benefits of different exercise intensities for elderly people with cognitive decline,and there is a lack of evidence to fix the optimal exercise intensity.

关 键 词：认知衰弱 运动 认知功能 身体功能 系统评价与Meta分析 

分 类 号：R473.74[医药卫生—护理学]