Intrinsic kinetics of catalytic hydrogenation of 2-nitro-4-acetylamino anisole to 2-amino-4-acetylamino anisole over Raney nickel catalyst  

作　　者：Xiangyang Cui Xin Zhang Baoju Wang Yuqi Sun Haikui Zou Guangwen Chu Yong Luo Jianfeng Chen 

机构地区：[1]State Key Laboratory of Organic-Inorganic Composites,Research Center of the Ministry of Education for High Gravity Engineering and Technology,Beijing University of Chemical Technology,Beijing 100029,China [2]School of Chemistry and Chemical Engineering,Shandong University of Technology,Zibo 255000,China

出　　处：《Chinese Journal of Chemical Engineering》2023年第12期1-8,共8页中国化学工程学报（英文版）

基　　金：the National Natural Science Foun-dation of China(22022802 and 22288102).

摘　　要：The catalytic hydrogenation of 2-nitro-4-acetylamino anisole(NMA)is a less-polluting and efficient method to produce 2-amino-4-acetamino anisole(AMA).However,the kinetics of catalytic hydrogenation of NMA to AMA remains obscure.In this work,the kinetic models including power-law model and Langmuir-Hinshelwood-Hougen-Watson(LHHW)model of NMA hydrogenation to AMA catalyzed by Raney nickel catalyst were investigated.All experiments were carried out under the elimination of mass transfer resistance within the temperature range of 70–100°C and the hydrogen pressure of 0.8–1.5 MPa.The reaction was found to follow 0.52-order kinetics with respect to the NMA concentration and 1.10-order kinetics in terms of hydrogen pressure.Based on the LHHW model,the dual-site dissociation adsorption of hydrogen was analyzed to be the rate determining step.The research of intrinsic kinetics of NMA to AMA provides the guidance for the reactor design and inspires the catalyst modification.

关 键 词：Intrinsic kinetics 2-nitro-4-acetylamino anisole Catalytic hydrogenation Raney nickel catalyst 

分 类 号：TQ203.2[化学工程—有机化工] TQ246.1