光催化、电催化和生物催化在扁桃酸合成中的应用进展  

The Applications of Photocatalysis,Electrocatalysis and Biocatalysis in Mandelic Acid Synthesis

作　　者：曹尚 赵宝海 张晓虎 侯学振 Cao Shang;Zhao Baohai;Zhang Xiaohu;Hou Xuezhen(Jiangsu Yuanchuang Pharmaceutical R&D Co.,Ltd.,Lianyungang 222000,China)

机构地区：[1]江苏原创药物研发有限公司,江苏连云港222000

出　　处：《山东化工》2024年第1期95-97,共3页Shandong Chemical Industry

摘　　要：扁桃酸被认为是一种应用领域非常广泛的手性药物中间体和相关分解剂,具有很高的价值。结合可持续化学合成的需求和趋势,简要总结了扁桃酸的传统合成方法,探讨了光催化、电催化和生物催化在扁桃酸合成中的应用;概述了光催化、电催化和生物催化的基本原理和机制,在扁桃酸合成中的应用案例以及各自的优势和挑战;最后,展望了光催化、电催化和生物催化在扁桃酸合成中的未来发展方向和研究挑战;可以为扁桃酸合成的催化方法选择和优化提供参考。Mandelic acid is widely regarded as a valuable chiral drug intermediate and a relevant decarboxylating agent,with extensive applications.In light of the demand and trend for sustainable chemical synthesis,this paper provides a brief overview of traditional synthetic methods for mandelic acid and discusses the applications of photocatalysis,electrocatalysis,and biocatalysis in its synthesis.The basic principles and mechanisms of photocatalysis,electrocatalysis,and biocatalysis are outlined,along with application examples,advantages,and challenges in mandelic acid synthesis.Finally,future directions and research challenges for the development of photocatalysis,electrocatalysis,and biocatalysis in mandelic acid synthesis are discussed.This paper serves as a reference for the selection and optimization of catalytic methods in mandelic acid synthesis.

关 键 词：光催化 电催化 生物催化 扁桃酸合成 可持续化学合成 

分 类 号：TQ463[化学工程—制药化工]