早期经阴道彩超检查子宫内膜厚度联合血清β-HCG检测在宫外孕临床诊断中的应用  

Early detection of endometrial thickness by transvaginal ultrasonography combined with serum β-HCG detection in the clinical diagnosis of ectopic pregnancy

作　　者：张盼 江艳丽[1] 姜卫波 Zhang Pan;Jiang Yan-li;Jiang Wei-bo(Department of Ultrasound,The Second Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China)

机构地区：[1]河南科技大学第二附属医院超声科,河南洛阳471000

出　　处：《四川生理科学杂志》2024年第1期87-89,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:探讨早期经阴道彩超检查子宫内膜厚度联合血清β-人绒毛膜促性腺激素(β-human chorionic gonadotropin,β-HCG)检测在宫外孕临床诊断中的应用。方法:选取2018年3月至2021年3月收治的156例宫外孕患者作为宫外孕组,另同期选取在本院行体检的健康孕妇156例作为对照组。收集两组的临床资料,两组均行早期经阴道彩超检查记录子宫内膜厚度、收缩期最大血流速度(Peak systolic velocity,VS)、舒张末期流速(Enddiastolic velocity,VD)和阻力指数(Resistance index,RI),采用化学发光免疫法检测血清β-HCG水平。对比两组上述指标差异,并采用受试者工作曲线(Receiver operating characteristic,ROC)分析上述指标联合检测对宫外孕的诊断价值。结果:宫外孕组患者VS、VD和RI水平均高于对照组(P<0.05),子宫内膜厚度和血清β-HCG水平均低于对照组(P<0.05)。ROC分析显示,子宫内膜厚度、VS、VD、RI、血清β-HCG及其联合检测的曲线下面积(Receiver operating characteristic,AUC)分别为0.780、0.743、0.733、0.746、0.793和0.934,(P均<0.05)。结论:早期经阴道彩超检查子宫内膜厚度联合血清β-HCG检测可以提高宫外孕诊断的准确度,有助于及时发现异常并治疗。Objective:To investigate the clinical diagnosis of ectopic pregnancy by early transvaginal ultrasonography and detection of endometrial thickness combined with serum β-human chorionic gonadotropin(β-HCG).Methods:A total of 156 patients with ectopic pregnancy admitted from March 2018 to March 2021 were selected as the ectopic pregnancy group,and 156 healthy pregnant women who underwent physical examination in our hospital during the same period were selected as the control group.Clinical data of the two groups were collected.The endometrial thickness,peak systolic velocity(VS)and enddiastolic velocity(VS)were recorded by early transvaginal ultrasonography in both groups.VD and resistance index(RI),serum β-HCG levels were detected by chemiluminescence immunoassay.The difference of the above indexes between the two groups was compared,and the value of the combined detection of the above indexes in the diagnosis of ectopic pregnancy was analyzed by receiver operating characteristic(ROC).Results:VS,VD and RI levels in ectopic pregnancy group were higher than those in control group(P<0.05),endometrial thickness and serum β-HCG levels were lower than those in control group(P<0.05).ROC analysis showed that endometrial thickness,VS,VD,RI,serumβ-HCG and their combined detection of the receiver operating characteristic,AUC was 0.780,0.743,0.733,0.746,0.793 and 0.934,respectively,all P<0.05.Conclusion:Early transvaginal ultrasonography of endometrial thickness combined with serumβ-HCG detection can improve the accuracy of diagnosis of ectopic pregnancy,and help to timely detection and treatment of abnormalities.

关 键 词：阴道彩超检查 血清β-人绒毛膜促性腺激素 子宫内膜厚度 宫外孕 

分 类 号：R714.22[医药卫生—妇产科学]