AngioJet血栓清除与CDT在急性下肢深静脉血栓治疗中的效果对比  

Comparison of the Efficacy of AngioJet Thrombectomy and CDT in the Treatment of Acute Deep Venous Thrombosis of Lower Extremities

作　　者：陈敏 乐昌鋆 林海 王亮 CHEN Min;LE Changyun;LIN Hai;WANG Liang(Department of Vascular Surgery,Sanming Yong'an General Hospital,Sanming Fujian 366000,China)

机构地区：[1]三明市永安总医院血管外科,福建三明366000

出　　处：《中国卫生标准管理》2024年第2期130-133,共4页China Health Standard Management

摘　　要：目的对比分析AngioJet血栓清除与导管接触性溶栓(catheterdirected thrombolysis,CDT)治疗在急性下肢深静脉血栓中的效果。方法回顾性分析三明市永安总医院血管外科2017年1月—2022年1月收治的76例急性下肢深静脉血栓患者的临床资料。其中34例应用AngioJet血栓清除,作为AngioJet组;42例应用CDT治疗,作为CDT组。对比分析2组患者的血栓清除率、溶栓时间、尿激酶用量、住院时间、术后并发症发生率、12个月随访维拉塔评分(Villalta score,Villalta)的差异。结果AngioJet组Ⅰ级清除0例,Ⅱ级清除8例,Ⅲ级清除26例,CDT组Ⅰ级清除5例,Ⅱ级清除14例,Ⅲ级清除23例,AngioJet组血栓清除率优于CDT组,差异有统计学意义(P<0.05);2组在溶栓时间、尿激酶用量、住院时间和术后血红蛋白尿发生率上比较,差异有统计学意义(P<0.05)。结论AngioJet血栓清除疗效优于CDT,能明显减少溶栓时间和尿激酶用量,缩短住院时间。Objective To compare and analyze the efficacy of AngioJet thrombectomy and catheterdirected thrombolysis(CDT)in the treatment of acute deep vein thrombosis of lower extremities.Methods The clinical data of 76 patients with acute lower extremity deep vein thrombosis admitted to department of vascular surgery,Sanming Yong'an General Hospital from January 2017 to January 2022 were retrospectively analyzed.A total of 34 patients were treated with AngioJet thrombus removal as AngioJet group and 42 patients were treated with CDT as CDT group.The differences in the thrombus clearance rate,thrombolysis time,urokinase dosage,hospital stay,postoperative complication rate,and 12 month follow-up Villalta score(Villalta)between the two groups were compared and analyzed.Results In AngioJet group,0 cases were cleared in grade Ⅰ,8 cases were cleared in grade Ⅱ,26 cases were cleared in grade Ⅲ,in CDT group,5 cases were cleared in grade Ⅰ,14 cases were cleared in grade Ⅱ,and 23 cases were cleared in gradeⅢ.The thrombus clearance rate in AngioJet group was better than that in CDT group,with statistical significance(P<0.05).There were statistically significant differences in thrombolysis time,urokinase dosage,hospital stay and postoperative hemoglobinuria incidence between the two groups(P<0.05).Conclusion AngioJet has better thrombectomy efficacy than CDT,and can reduce thrombolysis time and urokinase dosage,thereby shortening hospital stay.

关 键 词：下肢深静脉血栓 AngioJet CDT 溶栓时间 尿激酶用量 血栓清除率 

分 类 号：R654[医药卫生—外科学]