辛开苦降方治疗脾虚气滞型功能性消化不良临床观察  

Clinical Observation on Treatment of Spleen Deficiency and Qi Stagnation Type Functional Dyspepsia by Xinkai kujiang Prescription

作　　者：邵家东 王睿清 孙博云 胡鸿毅[1] SHAO Jiadong;WANG Ruiqing;SUN Boyun;HU Hongyi(Longhua Hosipital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《西部中医药》2024年第2期141-144,共4页Western Journal of Traditional Chinese Medicine

基　　金：上海市科委科研计划项目(19401971500)。

摘　　要：目的:观察辛开苦降方治疗脾虚气滞型功能性消化不良(functional dyspepsia,FD)的临床疗效。方法:将70例脾虚气滞型FD患者随机分为观察组(辛开苦降组35例,后脱落1例)和对照组(健脾理气组35例,后脱落2例)。观察组采用辛开苦降方治疗,对照组采用健脾理气法治疗,两组疗程均为4周。观察两组证候疗效、汉密尔顿焦虑量表总评分疗效、单项证候积分及舌诊特征值。结果:证候总有效率观察组[78.79%(26/33)]高于对照组[55.88%(19/34)](P<0.05)。汉密尔顿焦虑量表评分总有效率观察组[72.73%(24/33)]高于对照组[50.00%(17/34)](P<0.05)。胃脘胀满、食少纳呆、善太息、情绪急躁易怒等症状积分差观察组大于对照组,差异有统计学意义(P<0.05)。观察组舌苔厚薄特征值、腐腻特征值高于对照组(P<0.01)。结论:辛开苦降方能有效缓解脾虚气滞型FD的临床症状,缓解焦虑情绪,提高舌苔厚薄特征值及舌苔腐腻特征值。Objective:To observe clinical effects of the treatment of spleen deficiency and Qi stagnation type functional dyspepsia(FD)by Xinkai kujiang prescription(pungent herbs to open,bitter ones to downbear in the prescription).Methods:Seventy patients with FD of spleen deficiency and Qi stagnation pattern were randomized into the observation group(35 cases in the group of Xinkai kujiang prescription,one case dropped out)and the control group(35 cases in the group of invigorating spleen and regulating Qi,two cases dropped out).The observation group was treated by Xinkai kujiang prescription,and the control group by the method of invigorating spleen and regulating Qi,the course of the treatment was four weeks.To observe clinical effects of syndromes,total scores of HAMA,single syndrome integrals and eigenvalue of tongue diagnosis between both groups.Results:Total effective rate of the syndromes in the observation group was[78.79%(26/33)],higher than[55.88%(19/34)]of the control group(P<0.05).Total effective rate of HAMD in the observation group was[72.73%(24/33)],higher than[50.00%(17/34)]of the control group(P<0.05).The observation group was greater than the control group in the scores of the symptoms including epigastric distention and fullness,poor appetite,long sighing,irritability,and the difference had statistical meaning(P<0.05).The observation group was higher than the control group in the eigenvalues of tongue coating(P<0.01).Conclusion:Xinkai kujiang prescription could effectively relieve clinical symptoms,alleviate anxiety,increase eigenvalues of tongue coating.

关 键 词：消化不良 功能性 脾虚气滞 辛开苦降方 焦虑 舌诊客观化 

分 类 号：R723.11[医药卫生—儿科]