广州地区成人网织红细胞相关参数参考区间的调查研究  

Investigation of reference intervals for adult reticulocyte parameters in Guangzhou

作　　者：何静[1] 熊铁[1] 何永建 刘志伟[1] 冯丽梅[1] 邱凯[1] 孙德华[1] HE Jing;XIONG Tie;HE Yong-jian;LIU Zhi-wei;FENG Li-mei;QIU Kai;SUN De-hua(Department of Laboratory Medicine,Nanfang Hospital,Southern Medical Univesity,Guangzhou 510515,Guangdong,CHINA)

机构地区：[1]南方医科大学南方医院检验科,广东广州510515

出　　处：《海南医学》2024年第2期249-251,共3页Hainan Medical Journal

摘　　要：目的 调查广州地区成人网织红细胞相关参数的参考区间。方法 选择2022年12月1日至2023年5月25日在南方医科大学南方医院体检的1 064名健康者进行网织红细胞检测,参数为网织红细胞计数(RET#)、网织红细胞百分比(RET%)、未成熟网织红细胞比率(IRF%)、低荧光网织红细胞百分比(LFR%)、中荧光网织红细胞百分比(MFR%)、高荧光网织红细胞百分比(HFR%)、网织红细胞血红蛋白量(RET-He),健康志愿者按性别分组。另外,收集男女健康者各20份静脉血,进行参考区间验证。结果 网织红细胞相关参数呈偏态分布(P<0.05),采用百分位数法建立参考区间,男性组RET%、RET#、IRF%、LFR%、MFR%、HFR%、RET-He的参考区间分别为0.93%~2.95%、(47.1~147.4)×10^(9)/L、5.60%~20.20%、79.86%~94.40%、5.00%~14.76%、0.30%~6.28%、32.60~37.88 pg,女性组以上参数参考区间分别为0.92%~2.64%、(41.57~118.56)×10^(9)/L、4.47%~18.53%、81.47%~95.53%、4.20%~13.47%、0.20%~5.67%、31.40~37.10 pg。男女组均通过参考区间验证。结论 初步调查了广州地区成人网织红细胞相关参数参考区间。Objective To investigate the reference intervals for adult reticulocyte parameters in Guangzhou.Methods A total of 1064 healthy adults were selected in Nanfang Hospital,Southern Medical University from Decem-ber 1st 2022 to May 25th 2023 for reticulocyte test,and reticulocyte count(RET#),reticulocyte percentage(RET%),im-mature reticulocyte fraction(IRF%),low fluorescence reticulocyte percentage(LFR%),medium fluorescence reticulo-cyte percentage(MFR%),high fluorescence reticulocyte percentage(HFR%),and reticulocyte hemoglobin(RET-He)were determined.The healthy adults were classified into male and female group.Besides,20 blood samples from male and female healthy adults were collected for the verification of reference intervals,respectively.Results Reticulo-cyte-related parameters showed skewed distribution(P<0.05).Reference intervals were established by percentile.The reference intervals of RET%,RET#,IRF%,LFR%,MFR%,HFR%,RET-He in males were 0.93%-2.95%,(47.10-147.40)×10^(9)/L,5.60%-20.20%,79.86%-94.40%,5.00%-14.76%,0.30%-6.28%,32.60-37.88 pg,while those in females were 0.92%-2.64%,(41.57-118.56)×10^(9)/L,4.47%-18.53%,81.47%-95.53%,4.20%-13.47%,0.20%-5.67%,31.40-37.10 pg.The reference intervals were verified in both males and females.Conclusion The reference intervals of reticulocyte parameters for adult in Guangzhou were investigated preliminarily.

关 键 词：广州地区 网织红细胞 网织红细胞血红蛋白量 参考区间 

分 类 号：R331.141[医药卫生—人体生理学]