孕妇妊娠晚期B族链球菌感染的影响因素及对妊娠结局的影响  

Influencing Factors of Group B Streptococcus Infection in Pregnant Women in the Third Trimester and Its Influence on Pregnancy Outcome

作　　者：高菊逸 李艳雯 马曌 杨伟康 Gao Juyi;Li Yanwen;Ma Zhao;Yang Weikang(Shenzhen Longhua District Maternal and Child Health Care Hospital,Shenzhen 518172,Guangdong Province,China)

机构地区：[1]深圳市龙华区妇幼保健院,广东深圳518172

出　　处：《中国社区医师》2023年第33期152-154,共3页Chinese Community Doctors

摘　　要：目的:分析孕妇妊娠晚期B族链球菌感染的影响因素及对妊娠结局的影响。方法:选取2022年1-12月于深圳市龙华区妇幼保健院产科进行产检的3 000例孕妇作为研究对象,均进行B族链球菌培养检测,根据检测结果分为观察组(B族链球菌感染阳性)与对照组(B族链球菌感染阴性),分析孕妇妊娠晚期B族链球菌感染的影响因素,并比较两组不良妊娠结局、新生儿不良结局发生情况。结果:3 000例孕妇B族链球菌阳性345例(11.50%),阴性2 655例(88.50%)。两组年龄、妊娠史、妊娠糖尿病患病率、妊娠高血压患病率比较,差异无统计意义(P>0.05);观察组流产史、体质量增加过多、生殖道感染占比高于对照组,差异有统计学意义(P<0.05)。多因素Logistic回归模型分析显示,有流产史、体质量增加过多、存在生殖道感染均为孕妇妊娠晚期B族链球菌感染的独立危险因素(P<0.05)。观察组宫内感染、胎儿窘迫、早产、羊水污染、产后出血发生率高于对照组,差异有统计学意义(P<0.05)。观察组新生儿感染、肺炎、窒息以及病理性黄疸发生率高于对照组,差异有统计学意义(P<0.05)。结论:孕妇妊娠晚期B族链球菌感染与有流产史、体质量增加过多、存在生殖道感染有关,对母婴健康产生不良影响,临床需高度重视孕妇B族链球菌感染的预防。Objective:To analyze the influencing factors of group B streptococcus infection in pregnant women in the third trimester and its influence on pregnancy outcome.Methods:From January 2022 to December 2022,three thousand pregnant women in the maternity department of Shenzhen Longhua District Maternal and Child Health Care Hospital were selected as the study objects,and all of them were tested for group B streptococcus culture.According to the test results,they were divided into observation group(positive for group B streptococcal infection)and control group(negative for group B streptococcal infection).The influencing factors of group B streptococcal infection in pregnant women in the third trimester were analyzed,and the incidence of adverse pregnancy outcomes and neonatal adverse outcomes between the two groups were compared.Results:Among 3000 pregnant women,345(11.50%)were positive for group B streptococcus and 2655(88.50%)were negative;There was no significant difference in age,gestational history,prevalence of gestational diabetes and gestational hypertension between the two groups(P>0.05);The proportion of abortion history,body mass increase and reproductive tract infection in observation group was higher than that in control group,the difference was statistically significant(P<0.05);Multivariate Logistic regression model analysis showed that history of abortion,excessive increase in body mass and presence of reproductive tract infection were independent risk factors for group B streptococcus infection in the third trimester of pregnancy(P<0.05);The incidence of intrauterine infection,fetal distress,premature delivery,amniotic fluid contamination and postpartum hemorrhage in the observation group was higher than that in the control group,with statistical significance(P<0.05);The incidence of neonatal infection,pneumonia,asphyxia and pathological jaundice in observation group was higher than that in control group,and the difference was statistically significant(P<0.05).Conclusion:Group B streptococcal infection

关 键 词：妊娠晚期 B族链球菌 妊娠结局 

分 类 号：R714.25[医药卫生—妇产科学]