干燥综合征中医治疗优势评价方法学探讨  

Methodological Evaluation of Advantages of Traditional Chinese Medicine Treatment of Sjögren's Syndrome

作　　者：刘文靖 武诗雅 刘瑞华[1] 周新尧[1] 焦娟[1] 刘英[2] 李泽光[3] 李振彬 张华东[1] 唐晓颇[1] 姜泉[1] LIU Wenjing;WU Shiya;LIU Ruihua;ZHOU Xinyao;JIAO Juan;LIU Ying;LI Zeguang;LI Zhenbin;ZHANG Huadong;TANG Xiaopo;JIANG Quan(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250000,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150000,China;980 Hospital of PLA Joint Logistics Support Force,Shijiazhuang 050000,China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]山东中医药大学附属医院,济南250000 [3]黑龙江中医药大学附属第一医院,哈尔滨150000 [4]解放军联勤保障部队980医院,石家庄050000

出　　处：《中国实验方剂学杂志》2024年第1期192-197,共6页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中国中医科学院科技创新工程项目(CI2021A01502,CI2021A01510);中央级公益性科研院所基本科研业务费专项(ZZ15-YQ-023);国家自然科学基金面上项目(82374285)。

摘　　要：筛选评价中医优势病种有助于进一步彰显中医药治疗的亮点,其评价方法应在尊重特定疾病的个体化基础上实现标准化和规范化。干燥综合征(SS)发病率逐年升高,但其发病机制不清楚,现代医学治疗存在生物制剂、免疫抑制剂疗效欠佳的临床困惑。中医药治疗SS,以疗效为导向,身心并调,中华中医药学会风湿病分会邀请领域内中、西医专家及循证医学专家组建各工作组,基于专家调查法和文献计量法对SS优势病种筛选与评价,确立SS为待遴选病种之一并搭建SS优势病种评价体系,最终经过会议讨论达成一致。现将中医药治疗SS优势评价方法全流程进行梳理、总结和思考,课题组发现第一,由于中药雾化这一干预措施临床应用广泛,丰富了中药给药方式,因此将其他非药物疗法修改为特色疗法后将其纳入;第二,确定疗效评价指标要以国际公认为考量,限于本身研究现状;第三,表述方法要突出中医天然优势,体现严谨性和标准规范化,确保精准客观,避免扩大化。为临床医师对其他优势病种探讨提供参考,以飨同道。Screening and evaluating the diseases responding specifically to traditional Chinese medicine(TCM)will help to highlight the advantages of TCM treatment,and the evaluation method should be standardized with consideration to the unique characteristics of the diseases.The incidence of Sjögren's Syndrome(SS)is increasing year by year,while the pathogenesis of this disease remains unclear.Modern therapies for this disease include biological agents and immunosuppressants,which generally have unsatisfactory efficacy.The TCM treatment of SS focuses on the harmony of the physical and mental health.The Rheumatology Branch of the China Association of Chinese Medicine organizes experts in TCM,Western medicine,and evidence-based medicine to form working groups.Delphi method and bibliometric method were used for analysis,and SS was selected as a disease responding specifically to TCM.Furthermore,the evaluation system was established for this disease,and the consensus regarding this disease was reached after seminar discussion.This paper summarized the whole process of the evaluation of the advantages of TCM treatment of SS.First,because TCM atomization is widely used in clinical practice and enriches TCM administration methods,this therapy is included after other non-drug therapies were taken as characteristic therapies.Second,the evaluation indicators of therapeutic effect should be determined with consideration to international acceptance and the current research status.Third,the expression method should be accurate,standardized,and objective,highlight the natural advantages of TCM,and avoid arbitrary extension.This paper provides a reference for clinicians to explore other diseases responding specifically to TCM.

关 键 词：干燥综合征 燥痹 中医药 优势病种 专家调查法 文献计量法 方法学 

分 类 号：R242[医药卫生—中医临床基础] R2-0[医药卫生—中医学] R2-031R593R24