中药三联疗法对盆腔炎患者中医证候积分及血清炎症指标的影响分析  

Analysis of influence of triple therapy of traditional Chinese medicine on traditional Chinese medicine syndrome score and serum inflammatory index in patients with pelvic inflammation

作　　者：覃海莹 QIN Hai-ying(Department of Obstetrics and Gynecology,Luoding Hospital of Traditional Chinese Medicine,Luoding 527200,China)

机构地区：[1]罗定市中医院妇产科,527200

出　　处：《中国现代药物应用》2024年第2期141-144,共4页Chinese Journal of Modern Drug Application

摘　　要：目的 探讨中药三联疗法对盆腔炎患者中医证候积分以及血清炎症指标的影响。方法 选取80例盆腔炎患者,随机分为观察组(40例)与对照组(40例)。对照组患者接受血府逐瘀口服液联合奥硝唑胶囊治疗,观察组在对照组基础上接受中药三联疗法(中药透入疗法+中药温敷+中药保留灌肠)治疗。治疗4周后,比较两组患者的临床疗效、中医证候积分及血清炎症指标[白细胞介素-2(IL-2)、肿瘤坏死因子-α(TNF-α)和C反应蛋白(CRP)]。结果 观察组治疗总有效率95.00%高于对照组的80.00%,差异有统计学意义(P<0.05)。观察组患者少腹刺痛、腰骶胀痛、带下异常、经期腹痛、月经不调、乳房胀痛、情志不舒积分及总分分别为(2.43±0.43)、(3.34±0.51)、(2.21±0.34)、(1.54±0.23)、(1.24±0.20)、(0.98±0.12)、(1.43±0.31)、(13.17±3.94)分,均低于对照组的(3.34±0.44)、(5.04±0.63)、(3.74±0.32)、(1.98±0.33)、(2.03±0.15)、(1.65±0.27)、(2.46±0.29)、(20.24±3.31)分,差异有统计学意义(P<0.05)。观察组患者血清IL-2(32.34±19.32)pg/ml、TNF-α(8.83±1.33)ng/L和CRP(5.84±1.02)mg/L均低于对照组的(67.97±11.03)pg/ml、(12.21±1.29)ng/L、(12.23±1.42)mg/L,差异有统计学意义(P<0.05)。结论 对盆腔炎患者进行中药三联疗法(中药透入疗法+中药温敷+中药保留灌肠)治疗,其综合疗效显著,能有效改善患者血清炎症指标和中医证候积分,对提升患者生活质量有一定价值,值得临床推广应用。Objective To explore the influence of triple therapy of traditional Chinese medicine on traditional Chinese medicine syndrome score and serum inflammatory index in patients with pelvic inflammation.Methods 80 patients with pelvic inflammatory disease were selected and randomly divided into the observation group(40 cases)and the control group(40 cases).The patients in the control group received Xuefu Zhuyu oral liquid combined with ornidazole capsule for treatment,while the patients in observation group received traditional Chinese medicine triple therapy(traditional Chinese medicine penetration therapy+traditional Chinese medicine warm compress+traditional Chinese medicine retention enema)on the basis of the control group.4 weeks after treatment,the clinical efficacy,traditional Chinese medicine syndrome scores and serum inflammatory index[interleukin-2(IL-2),tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)]of the two groups were compared.Results The total effective rate of 95.00%in the observation group was higher than that of 80.00%in the control group,and the difference was statistically significant(P<0.05).In the observation group,the scores of hypoabdominal tingling,lumbosacral distending pain,subband abnormality,abdominal pain during menstruation,irregular menstruation,breast distending pain and emotional discomfort and total score were(2.43±0.43),(3.34±0.51),(2.21±0.34),(1.54±0.23),(1.24±0.20),(0.98±0.12),(2.21±0.34),(1.43±0.31)and(13.17±3.94)points,which were lower than those of(3.34±0.44),(5.04±0.63),(3.74±0.32),(1.98±0.33),(2.03±0.15),(1.65±0.27),(2.46±0.29)and(20.24±3.31)points in the control group.The difference was statistically significant(P<0.05).The observation group had serum IL-2 of(32.34±19.32)pg/ml,TNF-αof(8.83±1.33)ng/L and CRP of(5.84±1.02)mg/L,which were lower than those of(67.97±11.03)pg/ml,(12.21±1.29)ng/L and(12.23±1.42)mg/L in the control group,and the difference was statistically significant(P<0.05).Conclusion The comprehensive therapeutic effect of t

关 键 词：盆腔炎 中药三联疗法 炎症因子 中医证候积分 

分 类 号：R271.9[医药卫生—中西医结合]