南通市肿瘤医院2007-2017年卵巢癌住院患者生存分析  

Analysis on survival of inpatients with ovarian cancer in Nantong Tumor Hospital from 2007 to2017

作　　者：陈海珍[1] 徐红[2] 王高仁 钱赟 倪倬健 朱健[5] 张爱红[6] 王书兰 韩建周 潘敏侠[9] 葛建娟[1] 王琴[1] 蔡波[2] 陈建国[5] Chen Haizhen;Xu Hong;Wang Gaoren;Qian Yun;Ni Zhuojian;Zhu Jian;Zhang Aihong;Wang Shulan;Han Jianzhou;Pan Minxia;Ge Jianjuan;Wang Qin;Cai Bo;Chen Jianguo(Cancer Institute,Affiliated Tumor Hospital of Nantong University,Nantong Tumor Hospital,Nantong 226361,China;Nantong Center for Disease Control and Prevention,Nantong 226007,China;Hai'an Center for Disease Control and Prevention,Hai'an 226600,China;Haimen Center for Disease Control and Prevention,Nantong 226100,China;Qidong Liver Cancer Institute,Qidong People's Hospital,Afiliated Qidong Hospital of Nantong University,Qidong 226200,China;Rudong Center for Disease Control and Prevention,Rudong 226400,China;Rugao Center for Disease Control and Prevention,Rugao 226500,China;Tongzhou Center for Disease Control and Prevention,Nantong 226300,China;Nantong Health College of Jiangsu Province,Nantong 226010,China)

机构地区：[1]南通市肿瘤医院南通大学附属肿瘤医院肿瘤研究所,南通226361 [2]南通市疾病预防控制中心,南通226007 [3]海安市疾病预防控制中心,海安226600 [4]南通市海门区疾病预防控制中心,南通226100 [5]启东肝癌防治研究所启东市人民医院南通大学附属启东医院,启东226200 [6]如东县疾病预防控制中心,如东226400 [7]如皋市疾病预防控制中心,如皋226500 [8]南通市通州区疾病预防控制中心,南通226300 [9]江苏省南通卫生高等职业技术学校,南通226010

出　　处：《中国肿瘤临床与康复》2023年第8期493-498,共6页Chinese Journal of Clinical Oncology and Rehabilitation

基　　金：江苏省南通市人口发展研究课题页(20220914);江苏省医院协会医院管理创新研究课题(JSYGY-3-2019-381)。

摘　　要：目的对2007-2017年南通市肿瘤医院卵巢癌住院患者进行生存分析,为卵巢癌综合防治、预后评价提供基本信息和依据.方法采用以医院为基础的肿瘤随访,结合现场以人群为基础的肿瘤随访方法,对南通市肿瘤医院住院患者中来自南通所辖各县(市)区的卵巢癌患者进行生存随访,随访截至2020年12月31日.以寿命表法计算观察生存率,用SPSS 22.0软件绘制生存率曲线,并采用Wilcoxon统计量Gehan值进行生存率比较.结果2007-2017年卵巢癌住院患者1342例,经随访获得恶性肿瘤生存结局1152例,随访成功率为85.84%.首次入院时年龄10~90岁,平均(55.42±12.65)岁;患者以35~59岁为主,共639例,占全部卵巢癌患者的55.47%.2007-2017年卵巢癌患者各年度分布呈明显上升趋势.1152例卵巢癌患者共住院6988次,中位住院6次.1、3、5和10年观察生存率分别为79.86%、54.69%、43.14%和32.45%.15~34岁、35~59岁、60~79岁、≥80岁组患者的5年生存率分别为80.48%、48.03%、32.00%和16.00%,各年龄组比较,差异有统计学意义(Gehan=64.378,P<0.01).2007-2017年南通所辖各县(市)区(海安市、海门区、启东市、如东县、如皋市、通州区)卵巢癌患者的5年生存率分别为41.59%、32.66%、36.27%、38.72%、44.07%及51.48%,差异有统计学意义(Gehan=16.291,P<0.01).结论2007-2017年南通市肿瘤医院卵巢癌患者以中青年为主,各年度住院分布呈明显上升趋势,卵巢癌生存率的年龄差异值得关注,卵巢癌综合防治能力有待提高.Objectives To analyze the survival of ovarian cancer cases in Nantong Tumor Hospital(NTH)in 2007-2017,in order to provide information and basis for comprehensive prevention of ovarian cancer control.Methods Inpatients with ovarian cancer hospitalized at NTH from counties and districts in Nantong area were traced,by combined methods of active-and passive follow-up.The closing date for the outcome was December 31,2020.Observed survival was calculated using the life table method performed by SPSS 22.0 Software;survival functions(curves)were plotted and compared.Wilcoxon statistic(Gehan)is used for test.Results The total number of records of ovarian cancer patients hospitalized from 2007 to 2017 was 7777,involving 1342 cases.Of which 1152 cases whose outcome was confirmed with an average rate of 85.84%.The ages at the time of first admission were between 10 to 90 years,with an average age of(55.42±12.65)years;the patients were mainly 35 to 59 years old,with a total of 639 cases,accounting for 55.47%of all cases of ovarian cancer.There was a significant upward trend in the annual distribution of patients with ovarian cancer from 2007 to 2017.The total number of hospitalizations for ovarian cancer was 1152,with an average of(6.07±4.88)and a median of 6.Observed survival rates of 1-,3-,5-,and 10-years were 79.86%,54.69%,43.14%,and 32.45%,respectively.The 5-year survival rates at age groups of 15-34,35-59,60-79,and 80 years or older were 80.48%,48.03%32.00%,and 16.0%,respectively,with a significant difference(Gehan=64.378,P<0.01).The 5-year survival rates of patients with ovarian cancer in Nantong area from 2007 to 2017 were 41.59%in HA,31.66%in HM,36.27%in QD,38.72%in RD,44.07%in RG,and 51.48%in TZ,respectively,with a statistical significance(Gehan=16.291,P<0.01).Conclusions Ovarian cancer patients hospitalized during 2007-2017 were mainly in the middle-aged and younger age group,with a significant upward trend.Age differences in ovarian cancer survival should deserve attention;the ability of comprehensive prevention

关 键 词：卵巢癌 肿瘤登记 随访 生存率 南通 

分 类 号：R737.31[医药卫生—肿瘤]