人血白蛋白联合茵栀黄颗粒辅治新生儿病理性黄疸疗效观察  

作　　者：陈家奇 

机构地区：[1]河南科技大学第一附属医院开元院区儿科,河南洛阳471003

出　　处：《实用中医药杂志》2023年第10期1962-1964,共3页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察人血白蛋白联合茵栀黄颗粒辅治新生儿病理性黄疸(PJON)的疗效。方法:86例随机分为观察组和对照组各43例。两组均给予蓝光照射联合茵栀黄颗粒治疗,观察组加用人血白蛋白静脉滴注,均持续治疗5天。结果:总有效率观察组高于对照组(P<0.05)。胎便排空时间、黄疸消退时间及住院时间观察组短于对照组(P<0.05)。治疗后血清TBil、DBil、γ-GGT和AST水平观察组均低于对照组(P<0.05),观察组CD4^(+)、CD4^(+)/CD8^(+)高于对照组、CD8^(+)低于对照组(P<0.05)。不良反应发生率观察组低于对照组(P<0.05)。结论:人血白蛋白联合茵栀黄颗粒辅治PJON可提高疗效。Objective:To observe the curative effect of human serum albumin combined with Yinzhihuang Granules in the treatment of neonatal pathological jaundice(PJON).Methods:Eighty-six cases were randomly divided into the observation group and the control group,43 cases in each group.Both groups were treated with blue light irradiation combined with Yinzhihuang granules,and the observation group were treated with intravenous drip of human albumin for 5 days.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).The meconium emptying time,jaundice regression time and hospitalization time in the observation group were shorter than those in the control group(P<0.05).After treatment,the levels of serum TBil,DBil,γ-GGT and AST in the observation group were lower than those in the control group(P<0.05).CD4^(+)and CD4^(+)/CD8^(+)in the observation group were higher than those in the control group,and CD8^(+)was lower than that in the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion:Human serum albumin combined with Yinzhihuang Granules could improve the curative effect in the treatment of PJON.

关 键 词：新生儿病理性黄疸 人血白蛋白 茵栀黄颗粒 对照治疗观察 

分 类 号：R722.17[医药卫生—儿科]