再造生血胶囊联合琥珀酸亚铁治疗气血两虚证型缺铁性贫血的疗效观察  

Clinical observation of Zaizao Shengxue Capsules combined with ferrous succinate in treatment of iron deficiency anemia of deficiency of both qi and blood

作　　者：靳铎 徐清华 康廷干 李文静 李甜甜 JIN Duo;XU Qing-hua;KANG Ting-gan;LI Wen-jing;LI Tian-tian(Department of Hematology,Taihe County People's Hospital,the Taihe Hospital of Wannan Medical College,Fuyang 236600,China;TCM Internal Medicine,Taihe County People's Hospital,the Taihe Hospital of Wannan Medical College,Fuyang 236600,China)

机构地区：[1]太和县人民医院,皖南医学院附属太和医院血液内科,安徽阜阳236600 [2]太和县人民医院,皖南医学院附属太和医院中医内科,安徽阜阳236600

出　　处：《现代药物与临床》2023年第12期3102-3105,共4页Drugs & Clinic

摘　　要：目的探讨再造生血胶囊联合琥珀酸亚铁治疗气血两虚证型缺铁性贫血的临床效果。方法选取2019年1月—2023年3月太和县人民医院收治的120例气血两虚缺铁性贫血患者,随机分为对照组(60例)和治疗组(60例)。对照组口服琥珀酸亚铁片,0.1 g/次,3次/d。治疗组在对照组基础上口服再造生血胶囊,5粒/次,3次/d。两组患者治疗3个月。观察两组患者临床疗效,比较治疗前后两组铁离子(SI)、血清铁蛋白(SF)和血红蛋白(HGB)水平及中医证候积分。结果治疗后,治疗组患者总有效率较对照组显著升高(98.33%vs 88.33%,P<0.05)。治疗后,两组SI、SF及HGB水平显著高于治疗前(P<0.05),且治疗组明显高于对照组(P<0.05)。治疗后,两组中医证候积分显著低于治疗前(P<0.05),且治疗组明显低于对照组(P<0.05)。结论再造生血胶囊联合琥珀酸亚铁可有效提高气血两虚证型缺铁性贫血患者铁蛋白及血红蛋白水平,以及改善此类患者中医证候。Objective To explore the clinical effect of Zaizao Shengxue Capsules combined with ferrous succinate in treatment of iron deficiency anemia of deficiency of both qi and blood.Methods Patients(120 cases)with iron deficiency anemia of deficiency of both qi and blood from January 2019 to March 2023 were randomly divided into control(60 cases)and treatment(60 cases)group.Patients in the control group were po administered with Ferrous Succinate Tablets,0.1 g/time,three times daily.Patients in the treatment group were po administered with Zaizao Shengxue Capsules on the basis of the control group,5 grains/time,three times daily.Patients in two groups were treated for 3 months.After treatment,the clinical evaluation was evaluated,SI,SF and HGB levels,TCM syndrome scores in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was significantly higher than that of the control group(98.33%vs 88.33%,P<0.05).After treatment,the levels of SI,SF and HGB in two groups were significantly higher than those before treatment(P<0.05),and which in the treatment group were significantly higher than those in the control group(P<0.05).After treatment,the TCM syndrome score in two groups was significantly lower than that before treatment(P<0.05),and which in the treatment group was significantly lower than that of the control group(P<0.05).Conclusion Zaizao Shengxue Capsules combined with ferrous succinate can effectively improve the levels of ferritin and hemoglobin in patients with iron deficiency anemia of deficiency of both qi and blood,and improve the TCM syndrome.

关 键 词：再造生血胶囊 琥珀酸亚铁片 气血两虚证型 缺铁性贫血 血清铁蛋白 血红蛋白 中医证候积分 

分 类 号：R973[医药卫生—药品]