炙甘草汤加减联合美托洛尔治疗非瓣膜性房颤临床观察  

作　　者：张可农 

机构地区：[1]湖北省公安县中医医院内二科(心病科),湖北公安434300

出　　处：《实用中医药杂志》2024年第1期54-56,共3页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察炙甘草汤加减联合美托洛尔治疗非瓣膜性房颤(NVAF)的效果。方法:92例随机分为两组各46例。两组均给予美托洛尔治疗,观察组加用炙甘草汤加减。结果:总有效率观察组高于对照组(P<0.05)。治疗后观察组心悸怔忡、五心烦热、气短乏力、失眠多梦评分及左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、左房内径(LAD)、ICAM-1低于对照组,左室射血分数(LVEF)、tPA高于对照组(P<0.05)。两组不良反应相当(P>0.05)。结论:炙甘草汤加减联合美托洛尔治疗NVAF效果较好,且无严重不良反应。Objective:To observe the effect of modified Zhigancao Decoction combined with metoprolol in the treatment of non-valvular atrial fibrillation(NVAF).Methods:Ninety-two cases were randomly divided into two groups,46 cases in each group.Both groups were treated with metoprolol,and the observation group were treated with modified Zhigancao Decoction in addition.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the scores of palpitation,burning sensation of five centers,shortness of breath,insomnia and dreaminess,left ventricular end-systolic diameter(LVESD),left ventricular end-diastolic diameter(LVEDD),left atrial diameter(LAD)and ICAM-1 in the observation group were lower than those in the control group,and left ventricular ejection fraction(LVEF)and tPA were higher than those in the control group(P<0.05).The adverse reactions of the two groups were similar(P>0.05).Conclusion:Modified Zhigancao Decoction combined with metoprolol is effective in the treatment of NVAF,without serious adverse reactions.

关 键 词：非瓣膜性房颤 炙甘草汤 美托洛尔 

分 类 号：R541.75[医药卫生—心血管疾病]