Reshaping the imprinting strategy through the thermo-responsive moiety-derived“deep eutectic solvents”effect  

作　　者：Huihuang Xiong Yiqun Wan Yong Fan Mengjia Xu Aiping Yan Yushan Zhang Qifei Jiang Hao Wan 

机构地区：[1]State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China [2]School of Chemistry and Chemical Engineering,Nanchang University,Nanchang 330031,China [3]Jiangxi Province Key Laboratory of Modern Analytical Science,Nanchang University,Nanchang 330031,China [4]Department of Computer Science,University of California Irvine,Irvine 92697,United States

出　　处：《Chinese Chemical Letters》2024年第1期441-445,共5页中国化学快报（英文版）

基　　金：National Key Research and Development Project(No.2019YFC1604904);National Natural Science Foundation of China(No.32101212);Natural Science Foundation of Jiangxi(No.20224ACB215009);Research Program of State Key Laboratory of Food Science and Technology in Nanchang University(No.SKLF-ZZB-202127).

摘　　要：As a new concept having emerged in last few years,the“deep eutectic solvents”(DESs)effect integrated into the imprinting technology inevitably exposes design limitations of stimuli-responsive molecularly imprinted polymers(MIPs),as well as inadequate analysis of the adsorption performance of MIPs.Herein,a simple yet defined N-isopropylacrylamide/(3-acrylamidopropyl)trimethylammonium chloride(NIPAM/APTMAC)binary DESs system was proposed to prepare intelligent MIPs with thermo-sensitivity.Accordingly,magnetic and thermo-responsive MIPs based on functional monomers-derived DESs(TMDESs-MIPs1)were synthesized,revealing DESs effect-regulated affinity/kinetics for the enhanced adsorption capability,eco-friendly thermo-regulated elution for high release efficiency,and simple magnetic separation,along with superior selectivity to rhein(RH)and good regeneration ability.TM-DESs-MIPs1 were utilized to extract RH from Cassiae semen samples coupled with high performance liquid chromatography(HPLC),yielding satisfactory recoveries(79.47%−110.82%)and low limits of detection(LOD)(16.67μg/L).Another two kinds of MIPs adopting the thermo-responsive moiety-derived DESs effect strategy further demonstrated great applicability of such intelligent MIPs for analyses of complicated samples.

关 键 词：Deep eutectic solvents Molecularly imprinted polymers Magnetic THERMO-RESPONSIVE Thermo-regulated elution 

分 类 号：O631.3[理学—高分子化学]