2016—2021年云南省贡山县人群土源性线虫感染监测结果分析  

Surveillance on soil-transmitted helminth infections in Gongshan County of Yunnan Province from 2016 to 2021

作　　者：段承丽 何冬梅 杨舒 张妍黎 罗自荣 雄碧才 字金荣 彭佳[4] 吴方伟[4] DUAN Chenli;HE Dongmei;YANG Shu;ZHANG Yanli;LUO Zirong;XIONG Bicai;ZI Jinrong;PENG Jia;WU Fangwei(Nujiang Center for Disease Control and Prevention,Lushui 673199,Yunnan,China;Nujiang People’s Hospital,Lushui 673199,Yunnan,China;Gongshan Center for Disease Control and Prevention,Gongshan 673599,Yunnan,China;Yunnan Institute of Parasitic Diseases,Pu’er 665000,China)

机构地区：[1]怒江傈僳族自治州疾病预防控制中心,云南泸水673199 [2]怒江傈僳族自治州人民医院,云南泸水673199 [3]贡山独龙族怒族自治县疾病预防控制中心,云南贡山673599 [4]云南省寄生虫病防治所,普洱665000

出　　处：《中国寄生虫学与寄生虫病杂志》2023年第6期766-771,共6页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：为了解贡山县人群土源性线虫感染现状及流行趋势,2016—2021年,根据《全国肝吸虫病和土源性线虫病监测方案(试行)》要求,按照地理方位将贡山县划分为东、西、南、北、中5个片区,每年在每个片区随机抽取1个乡(镇)的1个行政村为调查村,调查对象为调查村3岁及以上本地常住人口。收集调查对象的粪样,采用改良加藤厚涂片法检查土源性线虫虫卵并计数,采用试管滤纸培养法鉴别钩虫虫种,3~9岁儿童加做透明胶纸肛拭法检查蛲虫卵。记录感染虫种和人数,计算感染率,感染率间比较采用卡方检验。共粪检6175人,土源性线虫感染928例,总感染率为15.03%(928/6175),其中蛔虫、鞭虫、钩虫和蛲虫的感染率分别为7.92%(489/6175)、8.87%(548/6175)、3.27%(202/6175)和0.19%(12/6175)。透明胶纸肛拭法检查3~9岁儿童823人,检出蛲虫感染6例。对202例钩虫感染者采用试管滤纸培养法进行钩虫虫种鉴别,其中美洲钩虫感染89例,十二指肠钩虫感染72例,两者混合感染1例,分别占44.06%(89/202)、35.64%(72/202)和0.50%(1/202)。钩虫、蛔虫和鞭虫轻度感染者分别占81.19%(164/201)、69.33%(339/489)和78.29%(429/548)。2016—2021年贡山县各年度人群土源性线虫感染率分别为38.78%(389/1003)、14.76%(156/1057)、6.53%(68/1042)、13.15%(134/1019)、11.89%(121/1018)和5.79%(60/1036),各年度间感染率差异有统计学意义(χ^(2)=581.98,P<0.01)。调查的5个乡(镇)中,独龙江乡人群土源性线虫感染率最高,为32.07%(398/1241),茨开镇最低,为9.09%(112/1232),不同乡(镇)间人群土源性线虫感染率差异有统计学意义(χ^(2)=359.24,P<0.01)。女性感染率17.81%(637/3577)高于男性感染率11.20%(291/2598)(χ^(2)=51.49,P<0.01)。各年龄组均有感染者,以3~9岁年龄组土源性线虫感染率最高(28.21%,244/865);民族分布以独龙族人群土源性线虫感染率最高(30.39%,392/1290);职业分布以儿童土源性线虫感染率最高(27.78%,170/To understand the prevalence and transmission of soil-transmitted helminth(STH)infection in Gongshan County.From 2016 to 2021,according to the National Surveillance Program for Liver Fluke Diseases and Soil-transmitted Nematodes(Pilot).The Gongshan County were selected from five areas(east,west,south,north and central).From each of the areas,a township was randomly selected,and then an administrative village was selected from each township as the surveillance site every year.Over 200 permanent residents above 3 years old were cluster sampled from each administrative village and no less than 1000 residents were included every year.Fecal samples were collected from the participants for examining and counting STH eggs using the modified Kato-Katz thick smear method to calculate the infection rate.Hookworm egg-positive samples were further identified for species by test tube-filter paper culture method.The eggs of Enterobius vermicularis were detected by the cellophane tape method in children aged 3-9 years.The species and number of infected were recorded,and the infection rate was calculated.The infection rate between groups was compared by the Chi-square test.The fecal samples from 6175 residents were examined with 928 samples infected with STH.The total infection rate was 15.03%(928/6175).The infection rates of hookworm,Ascaris lumbricoides,whipworm and Enterobius vermicularis were 3.27%(202/6175),7.92%(489/6175),8.87%(548/6175)and 0.19%(12/6175)respectively.The E.vermicularis eggs were detected by the cellophane tape method in children aged 3-9 years.A total of 823 children were examined and 6 were infected.A total of 202 cases of hookworm infection were identified by the test tube filter method.Among them,89 cases were infected with Necator americanus,72 cases were infected with Ancylostoma duodenale and 1 case was infected with both,accounting for 44.06%(89/202),35.64%(72/202)and 0.50%(1/202),respectively.Minor with hookworm,A.lumbricoides and whipworm infections accounted for 81.19%(164/201,69.33%(339/489)and

关 键 词：土源性线虫 感染率 监测 贡山县 

分 类 号：R532.1[医药卫生—内科学]