血友病伴尿毒症患者的透析及透析通路问题--6例报道并文献复习  

Dialysis and dialysis access issues in hemophilia patients with end-stage renal disease:a report of 6 cases and literature review

作　　者：刘炳岩[1] 蔡华聪[2] 周紫娟[1] 王颖[1] 胡燕[1] 陈之淳 王海云[1] 陈丽萌[1] Liu Bingyan;Cai Huacong;Zhou Zijuan;Wang Ying;Hu Yan;Chen Zhichun;Wang Haiyun;Chen Limeng(Department of Nephrology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China;Department of Hematology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医院肾内科,北京100730 [2]中国医学科学院北京协和医院血液内科,北京100730

出　　处：《中华肾脏病杂志》2023年第12期927-931,共5页Chinese Journal of Nephrology

摘　　要：血友病伴尿毒症患者进行肾脏替代治疗以及透析通路围术期处理存在一定的困难和挑战。该文总结了北京协和医院自2000年1月1日至2023年3月31日诊治的6例此类患者的经验,均行维持性腹膜透析,其中3例行短期血液透析或连续性静脉-静脉血液滤过治疗,期间进行透析通路建立手术或操作11次,未发生严重出血或血栓事件。结合文献复习,总结此类患者相关各类透析通路的使用要点,以期为其肾脏替代治疗路径提供借鉴。Renal replacement therapy and perioperative management have difficulties in hemophilia patients with end-stage renal disease.The paper summarized the diagnosis and treatment experience of six hemophilia patients complicated with end-stage renal disease from January 1,2000 to March 31,2023 in Peking Union Medical College Hospital.Among 6 patients treated with peritoneal dialysis,3 were treated with hemodialysis or continuous venous-venous hemodialysis.Altogether 11 dialysis access procedures were conducted successfully,and no serious bleeding or thrombotic events.In further conjunction with literature review,the paper summarized the key points of dialysis access appliance relevant to such patients,to provide reference for renal replacement treatment paths.

关 键 词：血友病A 肾功能衰竭 慢性 腹膜透析 透析通路 血液透析 围术期处理 

分 类 号：R554.1[医药卫生—血液循环系统疾病] R692.5[医药卫生—内科学]