医用放射性同位素制备的现状与展望  

Present Situation and Prospect of Medical Radioactive Isotope Preparation

作　　者：刘鹏[1,2] 杜克泽 马福秋 吉明波 王跃霖[2] 桂云阳 李蕴财 LIU Peng;DU Keze;MA Fuqiu;JI Mingbo;WANG Yuelin;GUI Yunyang;LI Yuncai(Yantai Research Institute,Harbin Engineering University,Yantai 265500,China;College of Nuclear Science and Technology,Harbin Engineering University,Harbin 150006,China)

机构地区：[1]哈尔滨工程大学烟台研究(生)院,烟台265500 [2]哈尔滨工程大学核科学与技术学院,哈尔滨150006

出　　处：《同位素》2024年第1期77-90,共14页Journal of Isotopes

基　　金：烟台市科技计划项目(2022JCYJ042);烟台新旧动能转换研究院开放基金(YTDNY20220425-02)。

摘　　要：医用放射性同位素可用于诊断、治疗疾病。随着国家的重视与人民的渴望,医用放射性同位素生产领域将迎来快速发展时期,本研究对医用放射性同位素的生产方式进行总结,着重介绍99Mo、125I、131I、177Lu、89Sr、18F、68Ga、225Ac等医用同位素制备方法和发展情况,结合2021年国家八部委联合发布的《医用同位素中长期发展规划(2021—2035年)》,对国内放射性医用同位素的现状进行总结。Medical radioactive isotopes can be used for diagnosis,treatment of diseases,and production of radiopharmaceuticals.With the attention of the country and the desire of the people,the field of medical radioactive isotope production will soon enter a period of rapid development.This article summarizes the production methods of medical radioactive isotopes and divides them into three categories:reactor,accelerator,and other methods.It focuses on the preparation methods and development status of medical isotopes such as 99 Mo,125 I,131 I,177 Lu,89 Sr,18 F,68 Ga,and 225 Ac.Combining with the“Medium-to-Long-Term Development Plan for Medical Isotopes(2021-2035)”jointly published by eight ministries and commissions in 2021,this article provides a certain degree of summary of the current situation of domestic radioactive medical isotopes.It can provide researchers with development ideas for a period of time in the future and propose certain development trends and prospects based on the current development situation.

关 键 词：放射性药物 医用放射性同位素 加速器 反应堆 

分 类 号：TL50[核科学技术—核技术及应用] TL99