泛甲壳动物激素调控卵黄蛋白原合成的分子机制研究进展  

Research progress on molecular mechanism of hormone regulation of vitellogenin synthesis in Pancrustacea

作　　者：谢持真 陆颖 邱高峰[1,2] XIE Chizhen;LU Ying;QIU Gaofeng(Key Laboratory of Genetic Resources for Freshwater Aquaculture and Fisheries,Ministry of Agriculture and Rural Affairs,College of Fisheries and Life Science,Shanghai Ocean University,Shanghai 201306,China;National Demonstration Center for Experimental Fisheries Science Education,Shanghai Engineering Research Center of Aquaculture,Shanghai Ocean University,Shanghai 201306,China)

机构地区：[1]上海海洋大学水产与生命学院,农业农村部淡水水产种质资源重点实验室,上海201306 [2]上海海洋大学,上海水产养殖工程技术研究中心,水产科学国家级实验教学示范中心,上海201306

出　　处：《水产学报》2024年第2期1-15,共15页Journal of Fisheries of China

基　　金：国家自然科学基金(41976103);国家重点研发计划(2018YFD0900201)。

摘　　要：甲壳动物和昆虫由于进化上亲缘关系近,被统称泛甲壳动物,大多数泛甲壳动物卵黄蛋白原为雌性特异性蛋白,是卵母细胞中储存的卵黄蛋白的前体,可为胚胎发育提供营养和能量,是决定繁殖性能的关键因素,在生殖发育中起着十分重要的作用。已有研究证明,调控泛甲壳动物卵黄蛋白原的主要激素有保幼激素、蜕皮激素、神经肽和胰岛素样肽等。昆虫保幼激素和蜕皮激素发挥促进作用,而神经肽和胰岛素样肽对卵黄蛋白原合成的调控作用因种类不同而存在不同。除了以上激素,甲壳动物特有的眼柄高血糖激素家族以及促雄腺激素(IAG)对卵黄蛋白原的合成起负调控作用。本文总结了近年来泛甲壳动物卵黄蛋白原合成调控机制的相关研究,概括并比较了调控昆虫与甲壳动物的卵黄蛋白原合成的主要激素及调控机制,为养殖虾蟹甲壳动物生殖调控相关研究提供参考。Crustaceans and insects are close in evolution and referred to as pancrustaceans.Most vitellogenin is a female-specific protein,which is the precursor of vitellin stored in oocytes.Vitellogenin plays a key role in reproductive success.It has been known that juvenile hormone,molting hormone,neuropeptide and insulin-like peptide are the main factors for regulating vitellogenin synthesis in pancrustaceans.The juvenile hormone and ecdysone exert promoting effect on vitellogenesis in insects,while the effect of neuropeptides and insulin-like peptides on the vitellogenesis in a species-specific manner.In addition to the above hormones,the crustacean unique hormones,such as eyestalk hyperglycemic hormone(CHH)family and insulin-like androgenic gland hormone(IAG),have inhibitory effects on the vitellogenin synthesis.This review summarized the research progress on the regulatory mechanism of vitellogenin synthesis in pancrustaceans,and make detail comparisons of the main hormones and their regulation of vitellogenin synthesis between insects and crustaceans,providing a valuable reference for future studies on reproduction control in cultivated decapod crustaceans.

关 键 词：甲壳动物 昆虫 卵黄蛋白原 调控机制 

分 类 号：S966.1[农业科学—水产养殖]