过敏性紫癜患儿维生素D含量的分析  

Analysis of Vitamin D in Children withHenoch-Schonlein Purpura

作　　者：刘四香 黄永坤[2] 世淑兰 孙晶晶 罗丽丝 王黎 凌昱[1] LIU Sixiang;HUANG Yongkun;SHI Shulan;SUN Jingjing;LUO Lisi;WANG Li;LING Yu(Dept.of Children Healthcare,Kunming Children’s Hospital,Kunming Yunnan 650034;Dept.of Pediatrics,The 1st Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650032;Dept.of Laboratory,Kunming Children’s Hospital,Kunming Yunnan 650034,China)

机构地区：[1]昆明市儿童医院儿保科,云南昆明650034 [2]昆明医科大学第一附属医院儿科,云南昆明650032 [3]昆明市儿童医院检验科,云南昆明650034

出　　处：《昆明医科大学学报》2024年第1期133-135,共3页Journal of Kunming Medical University

基　　金：昆明市卫生科技人才培养项目医学科技学科后备人才培养计划(千工程)基金资助项目[2022-SW(后备)-23]。

摘　　要：目的分析过敏性紫癜(henoch-schonlein purpura,HSP)患儿维生素D含量的变化。方法选取2022年7月至2023年7月在昆明市儿童医院就诊,符合HSP诊断的130例患儿作为研究对象,正常对照组选取同时期在昆明市儿童医院儿保科体检的100例健康儿童。收集HSP患儿及正常对照组儿童的血液标本,经昆明金域医学检验所测定各组儿童血清25(OH)D含量。结果HSP患儿血清25(OH)D含量较正常对照组儿童降低,差异有统计学意义(P<0.01);HSP患儿维生素D不足率较正常对照组增高,差异有统计学意义(P<0.01)。结论HSP患儿易出现维生素D不足,维生素D的补充可能为HSP的治疗提供新思路。Objective To analyze the changes of vitamin D in children with Henoch-Schonlein purpura(HSP).Methods 130 children with HSP from Kunming Children’sHospital between July 2022-July 2023 were selected as the study subjects and 100 healthy children were selected during the same period as the control group.The blood samples were collected from the children with HSP and the healthy children.The content of vitamin D was measured by Kunming Kingmed Institute for Clinical Laboratory.Results The content of 25(OH)D in children with HSP was lower than that in healthy children,and the difference was statistically significant(P<0.01).The proportion of vitamin D insufficiency in children with HSP was higher than that in healthy children,and the difference was statistically significant(P<0.01).Conclusion The children with HSP are prone to vitamin D insufficiency.Vitamin D supplementation may provide a new method for the treatment of HSP.

关 键 词：维生素D 过敏性紫癜 儿童 

分 类 号：R72[医药卫生—儿科]