育龄期女性孕前膳食模式与新生儿出生体重的关联性研究  

Study on Association of Preconception Dietary Patterns with Neonate Birth Weight

作　　者：郭姝 潘娟 李妍 张珍 崔宁宁 葛妍妍 黄珊珊 朱慈华 杨雪锋[1] Guo Shu;Pan Juan;Li Yan(Department of Nutrition and Food Hygiene,Hubei Key Laboratory of Food Nutrition and Safety,MOE Key Laboratory of Environment and Health,School of Public Health,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Jiang’an Maternal and Child Health Hospital,Wuhan 430014,China)

机构地区：[1]华中科技大学同济医学院公共卫生学院营养与食品卫生学系,武汉430030 [2]武汉市江岸区妇幼保健院,武汉430014

出　　处：《华中科技大学学报（医学版）》2024年第1期52-58,共7页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：国家自然科学基金资助项目(No.82173511)。

摘　　要：目的 前瞻性地研究中国育龄期女性孕前膳食模式与新生儿出生体重之间的关联。方法 选取在武汉市江岸区妇幼保健院进行孕前优生检查的育龄期女性为研究对象进行问卷调查和随访。使用半定量食物频率问卷收集膳食摄入信息,主成分分析提取膳食模式(dietary patterns, DPs),利用修正的泊松回归或线性回归模型分析DPs和新生儿出生体重之间的关系。结果 最终纳入的221对母婴分析结果表明,在4种膳食模式中,遵循“坚果-禽肉”模式的女性分娩大于胎龄儿(large for gestational age, LGA)的风险较低(RR:0.25;95%CI:0.08~0.79),在男婴中更为明显(RR:0.14,95%CI:0.03~0.72)。结论 以坚果和禽肉为特征的孕前DP降低了分娩LGA的风险,分娩男婴时更为明显。育龄期女性应在怀孕前保持良好的饮食习惯,以保障胎儿正常生长发育,降低不良出生结局的风险。Objective To investigate the associations between preconception dietary patterns(DPs)among Chinese women of childbearing age and neonatal birth weight.Methods The subjects selected for the questionnaire survey and follow-up were women of childbearing age who underwent prenatal eugenic examination at Jiang’an Maternal and Child Health Hospital.Dietary intake information was collected using a semi-quantitative food frequency questionnaire,dietary patterns were extracted by principal component analysis,and the relationship between DPs and birth weight was analyzed by modified Poisson regression or linear regression models.Results The final analysis of 221maternal and infant pairs showed that women who followed the“nuts-poultry”pattern,one of the four dietary patterns,had a lower risk of delivering large for gestational age(LGA)infants(RR:0.25;95%CI:0.08—0.79),which was more pronounced in those who delivered male infants(RR:0.14;95%CI:0.03—0.72).Conclusion The risk of having LGA newborn is decreased in woman who takes a preconception dietary pattern characterized by nuts and poultry,which is more pronounced in those delivering male infants.Females of childbearing age should maintain good dietary habits before conception to ensure proper growth and development of the fetus and reduce the risk of adverse birth outcomes.

关 键 词：出生体重 膳食模式 队列研究 大于胎龄儿 孕前保健 

分 类 号：R172[医药卫生—妇幼卫生保健]