口服胃肠超声造影评价慢性肾病患者胃动力和胃壁形态改变的研究  

Research of oral contrast-enhanced gastrointestinal ultrasound in evaluation of gastric motility and gastric wall morphology changes in patients with chronic kidney disease

作　　者：杨赞峰 刘旭静[1] 侯跃会 杨云飞 YANG Zanfeng;LIU Xujing;HOU Yuehui;YANG Yunfei(Functional Department of the Seventh People's Hospital of Hebei Province,Baoding 073000,China)

机构地区：[1]河北省第七人民医院功能科,073000

出　　处：《中国煤炭工业医学杂志》2023年第6期607-611,共5页Chinese Journal of Coal Industry Medicine

基　　金：河北省2020年度医学科学研究课题计划项目(编号:20200622)。

摘　　要：目的采用口服胃肠超声造影对慢性肾病(CKD)患者胃动力和胃壁形态改变进行评价和研究。方法选取2019年3月—2023年3月河北省第七人民医院收治的105例CKD患者作为研究组,选取同期82例志愿者作为对照组,对二组研究对象的基线资料进行比较,采用口服胃肠超声造影对二组研究对象的胃排空率(GER)、胃排空时间(ET)、服用造影剂10min时胃窦动力指数(MI)、胃窦胃壁厚度和十二指肠胃窦反流(DGR)、胃壁层次清晰度进行检测和比较。结果研究组患者合并高血压、糖尿病比例和ET、胃窦胃壁厚度、DGR比例、胃壁层次模糊比例均高于对照组,GER、MI均低于对照组,差异均有统计学意义(P<0.05);随着CKD分期的升高,患者的GER、MI逐渐下降,ET、胃窦胃壁厚度、DGR比例、胃壁层次模糊比例逐渐升高,差异均有统计学意义(P<0.05)。研究组患者的GER、MI水平与CKD分期呈负相关关系(P<0.05),ET、胃窦胃壁厚度与CKD分期呈正相关关系(P<0.05)。结论CKD患者表现为胃动力和胃壁层次清晰度的下降,其病变程度与CKD分期具有相关性,采用口服胃肠超声造影检查能够对于CKD患者的胃肠功能进行定量评价,具有无创安全、费用低廉、可耐受度高的优势。Objective To evaluate and study the changes in gastric motility and gastric wall morphology in patients with chronic kidney disease(CKD)using oral contrast-enhanced gastrointestinal ultrasound.Methods One hundred and five CKD patients admitted to the Seventh People's Hospital of Hebei Province from March2019 to March 2023 were selected as a study group,and 82 volunteers during the same period were selected as a control group.The baseline data of the study subjects between two groups were compared.Oral gastrointestinal contrast-enhanced ultrasound was used to detectand compare the gastric emptying rate(GER),gastric emptying time(ET),gastric antral motility index(MI)at 10 minutes of administration of contrast agent,thickness of gastric antral wall as well as duodenogastric reflux(DGR)and clarity of gastric wall hierarchy.Results The proportions of patients with hypertension,diabetes and ET,thickness of gastric antral wall,the proportion of DGR,the proportion of fuzzy gastric wall hierarchy of the patients in the study group were higher than those in the control group,while GER and MI were lower than those in the control group,the differences were statistically significant(P<0.05);As the CKD stage increased,the patient's GER and MI gradually decreased,while ET,gastric antral wall thickness,DGR ratio,and proportion of fuzzy gastric wall hierarchy gradually increased,the differences were statistically significant(P<0.05).The levels of GER and MI in the study group were negatively correlated with CKD stage(P<0.05),while ET,gastric antral wall thickness were positively correlated with CKD stage(P<0.05).Conclusion CKD patients exhibit a decrease in gastric motility and clarity of gastric wall hierarchy,and the severity is correlated with CKD stage.Oral contrast-enhanced gastrointestinal ultrasound examination can quantitatively evaluate the gastrointestinal function of CKD patients,which has the advantages of non-invasive safety,low cost,and high tolerability.

关 键 词：口服胃肠超声造影 慢性肾病 胃动力 胃壁形态 胃肠功能紊乱 

分 类 号：R692.3[医药卫生—泌尿科学]