溶石排石汤联合常规西医方案治疗泌尿系小结石湿热下注证患者的疗效观察  

Therapeutic Effect of Rongshi Paishi Decoction Combined with Conventional Western Medicine on Small Urinary Calculi(Syndrome of Dampness-Heat Pouring Down)

作　　者：王天鹭 束永兵[2] WANG Tian-lu;SHU Yong-bing(The Second Department of Nephropathy,Lu′an Hospital of Traditional Chinese Medicine,Lu′an Anhui 237000;Department of Internal Medicine,Lu′an Hospital of Traditional Chinese Medicine,Lu′an Anhui 237000)

机构地区：[1]六安市中医院肾病二科,安徽六安237000 [2]六安市中医院内科,安徽六安237000

出　　处：《世界中西医结合杂志》2024年第1期129-133,共5页World Journal of Integrated Traditional and Western Medicine

基　　金：安徽省红十字会中医药传承创新发展研究项目(2021ZYYB18)。

摘　　要：目的探讨溶石排石汤联合常规西医治疗泌尿系小结石湿热下注证的临床疗效。方法选取2019年4月—2022年4月期间六安市中医院肾病二科收治的泌尿系小结石湿热下注证患者80例作为研究对象,按随机数字表法分为对照组和研究组,每组各40例。对照组予常规西医方案治疗,研究组在对照组基础上给予溶石排石汤治疗。治疗1个月后,观察比较两组患者治疗前后疼痛评分,结石排出率、结石排出时间和下移距离,以及临床疗效和不良反应发生率。结果治疗后两组患者VAS评分较治疗前降低,差异有统计学意义(P<0.05);且研究组低于对照组,差异有统计学意义(P<0.05)。治疗后研究组结石排出率60.00%(24/40)高于对照组37.50%(15/40),差异有统计学意义(χ^(2)=4.053,P=0.044);研究组结石下移率40.00%(16/40)低于对照组62.50%(25/40),差异有统计学意义(χ^(2)=4.053,P=0.044);研究组结石排出时间短于对照组,差异有统计学意义(P<0.05);结石下移距离长于对照组,差异有统计学意义(P<0.05)。治疗后研究组临床总有效率95.00%(38/40)高于对照组77.50%(31/40),差异有统计学意义(P<0.05)。治疗期间,研究组不良反应发生率与对照组比较,差异无统计学意义(P>0.05)。结论溶石排石汤联合常规西医治疗泌尿系小结石湿热下注证疗效显著,有利于加快患者排石,安全性高。Objective To observe the therapeutic effect of Rongshi Paishi Decoction combined with conventional Western medicine on small urinary calculi in the patients with the syndrome of dampness-heat pouring down.Methods Eighty patients with small urinary calculi(syndrome of dampness-heat pouring down)treated in the Second Department of Nephropathy of Lu′an Hospital of Traditional Chinese Medicine from April 2019 to April 2022 were selected and assigned into a study group and a control group according to the random number table,with 40 patients in each group.The control group was treated with conventional Western medicine,while the study group was additionally treated with Rongshi Paishi Decoction.The treatment lasted for a month.The Visual Analogue Scale(VAS)scores before and after treatment,stone excretion rate,time to stone discharge,and stone downward moving distance were determined.The clinical efficacy and the incidence of adverse reactions were compared between the two groups.Results After treatment,the VAS scores of the two groups were lower than those before treatment(P<0.05),and the VAS score in the study group was lower than that in the control group(P<0.05).The stone excretion rate in the study group was 60.00%(24/40),which was higher than that(37.50%,15/40)in the control group(χ^(2)=4.053,P=0.044).The proportion of stones moving downward in the study group was 40.00%(16/40),which was lower than that(62.50%,25/40)in the control group(χ^(2)=4.053,P=0.044).The study group had shorter time to stone discharge(P<0.05)and longer downward moving distance of stone than the control group(P<0.05).The total response rate in the study group was 95.00%(38/40),which was higher than that(77.50%,31/40)in the control group(P<0.05).The incidence of adverse reactions showed no significant difference between the two groups(P>0.05).Conclusion Rongshi Paishi Decoction combined with conventional Western medicine has a significant effect on small urinary calculi in the patients with the syndrome of dampness-heat pouring down,whi

关 键 词：泌尿系小结石 溶石排石汤 湿热下注证 结石排出时间 

分 类 号：R691.4[医药卫生—泌尿科学]