术后24 h内血清降钙素原水平对肺移植术后短期结局的预测价值  

Predictive value of serum procalcitonin level within 24 hours after operation for short-term outcomes of lung transplantation

作　　者：王慧敏[1] 王鑫[1] 赵丽丽[1] 朱金霞[1] 李晓莉[1] 冯敏[1] 郭铁[1] WANG Huimin;WANG Xin;ZHAO Lili;ZHU Jinxia;LI Xiaoli;FENG Min;GUO Tie(Surgical Intensive Care Unit,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052)

机构地区：[1]郑州大学第一附属医院外科重症监护室,郑州450052

出　　处：《郑州大学学报（医学版）》2024年第1期133-135,共3页Journal of Zhengzhou University(Medical Sciences)

摘　　要：目的:探讨术后24 h内血清降钙素原(PCT)水平对肺移植术后短期结局的预测价值。方法:回顾性分析2021年1月至2022年6月于郑州大学第一附属医院行肺移植术患者的资料,检测术后24 h内血清PCT水平。术后6个月内死亡30例,存活49例。结果:死亡组术后24 h内血清PCT水平1.330(0.384,7.225)ng/mL高于存活组0.430(0.135,1.185)ng/mL(P<0.05)。Logistic回归分析结果显示,术后24 h内血清PCT水平升高的肺移植患者术后6个月内死亡风险增加,OR(95%CI)为1.416(1.126~1.781)。术后24 h内血清PCT水平预测肺移植术后6个月内死亡的ROC曲线,AUC(95%CI)为0.711(0.587~0.835)。结论:术后24 h内血清PCT水平对肺移植术后短期结局具有一定的预测价值。Aim:To explore the predictive value of serum PCT level within 24 hours after operation for short-term outcomes of lung transplantation.Methods:Data of patients underwent lung transplantation in the First Affiliated Hospital of Zhengzhou University from January 2021 to June 2022 were retrospectively analyzed.Serum PCT level within 24 hours after operation was detected.During 6 months after operation,30 cases died,49 cases were survival.Results:The serum PCT level within 24 hours after operation were 1.330(0.384,7.225)ng/mL in the death group and 0.430(0.135,1.185)ng/mL in the survival group,and the difference was significant(P<0.05).Logistic regression analysis results showed that the short-term death risk of lung transplantation patients elevated with the increase of serum PCT level,and OR(95%CI)was 1.416(1.126-1.781).AUC(95%CI)of ROC curve of serum PCT level within 24 hours after operation to predict short-term death was 0.711(0.587-0.835).Conclusion:Serum PCT level within 24 hours after operation maybe have predictive value for the outcomes within 6 months after lung transplantation.

关 键 词：肺移植 降钙素原 短期结局 

分 类 号：R655.3[医药卫生—外科学]