在静脉镇静/麻醉中环泊酚会取代丙泊酚吗?  

Can ciprofol replace propofol in intravenous sedation/anesthesia?

作　　者：邓硕曾[1] 赵薇[2] 夏涵[1] 张彦丽[2] Deng Shuozeng;Zhao Wei;Xia Han;Zhang Yanli(Department of Anesthesiology,Dongfang Hospital Beijing University of Chinese Medicine,Beijing City 100078,China;Department of Pharmacy,Dongfang Hospital Beijing University of Chinese Medicine,Beijing City 100078,China)

机构地区：[1]北京中医药大学东方医院麻醉科,北京100078 [2]北京中医药大学东方医院药学部,北京100078

出　　处：《中华疼痛学杂志》2023年第6期921-922,共2页Chinese Journal Of Painology

摘　　要：环泊酚与丙泊酚相比,其注射痛发生率低,对呼吸和循环抑制程度轻,且环泊酚的镇静/麻醉剂量比丙泊酚相同镇静深度的剂量低(0.4~0.5 mg/kg比2.0 mg/kg)。那么,在静脉镇静/麻醉中环泊酚会取代丙泊酚吗?环泊酚扩大应用的关键在于进一步深入研究和降低成本。Compared with propofol,ciprofol has less injection pain and less respiration and circulation inhibition.The sedative/anesthetic dose of ciprofol is lower than that of propofol at the same sedative depth(0.4-0.5 mg/kg vs.2.0 mg/kg).So,can ciprofol replace propofol intravenous sedative/anesthetic?The key to expand the application of ciprofol may rely on in-depth research and cost reduction.

关 键 词：二异丙酚 环泊酚 安全性 镇静/麻醉 

分 类 号：R614[医药卫生—麻醉学]