阿托伐他汀治疗重症冠心病急性心肌梗死的心电图疗效及对患者心室重构与生命质量的影响  

Electrocardiogram efficacy of atorvastatin in the treatment of severe coronary heart disease with acute myocardial infarction and its effect on ventricular remodeling and quality of life

作　　者：蒋冬林 王明霞 赵鹏峰 JIANG Donglin;WANG Mingxia;ZHAO Pengfeng(Department of Cardiology,Red Star Hospital,13th Division,Xinjiang Production and Construction Corps,Hami,Xinjiang,839000,China)

机构地区：[1]新疆生产建设兵团第十三师红星医院心内科,新疆哈密839000

出　　处：《当代医学》2023年第28期132-135,共4页Contemporary Medicine

摘　　要：目的探讨阿托伐他汀治疗重症冠心病急性心肌梗死的心电图疗效及对患者心室重构与生命质量的影响。方法选取2019年3月至2021年2月新疆生产建设兵团第十三师红星医院收治的89例重症冠心病急性心肌梗死患者作为研究对象,根据随机摸球法分为A组(n=45)与B组(n=44)。A组给予阿托伐他汀治疗,B组给予瑞舒伐他汀治疗,比较两组心电图疗效、心室重构及生命质量。结果A组治疗总有效率较高于B组(P<0.05)。治疗后,两组左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)均短于治疗前,左心室舒张末期容积(LVEDV)均小于治疗前,左心室射血分数(LVEF)均高于治疗前,且A组LVEDD、LVESD均短于B组,LVEDV小于B组,LVEF高于B组(P<0.05)。治疗后,两组生活质量综合评定问卷(GQOL)评分均高于治疗前,且A组高于B组(P<0.05)。结论阿托伐他汀治疗重症冠心病急性心肌梗死患者,可改善心室重构,提高心电图疗效与患者生命质量。Objective To investigate the Electrocardiogram efficacy of atorvastatin in the treatment of severe coronary heart disease with acute myocardial infarction and its effect on ventricular remodeling and quality of life.Methods A total of 89 patients with severe coronary heart disease with acute myocardial infarction treated in Red Star Hospital,13th Division,Xinjiang Production and Construction Corps from March 2019 to Feb-ruary 2021 were selected as the study subjects,and they were divided into the group A(n=45)and the group B(n=44)according to random ball-stroke method.The group A was treated with atorvastatin,while the group B was treated with rosuvastatin,the electrocardiogram efficacy,ventricu-lar remodeling,and quality of life were compared between the two groups.Results The total effective rate in the group A was higher than that in group B(P<0.05).After treatment,left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)of the two groups were shorter than before treatment,left ventricular end-diastolic volume(LVEDV)was smaller than before treatment,left ventricular ejec-tion fraction(LVEF)was higher than before treatment,LVEDD and LVESD in the group A were shorter than the group B,and LVEDV was smaller than the group B,LVEF was higher than the group B(P<0.05).After treatment,the generic quality of life inventory(GQOL)scores of the two groups were higher than before treatment,and the group A was higher than the group B(P<0.05).Conclusion Atorvastatin in the treatment of severe coronary heart disease patients with acute myocardial infarction,can improve ventricular remodeling and promote the electrocardiogram efficacy and quality of life of patients.

关 键 词：阿托伐他汀 冠心病 急性心肌梗死 心电图疗效 心室重构 

分 类 号：R542.22[医药卫生—心血管疾病]