肺脏超声检查诊断心源性呼吸困难的Meta分析  

Lung ultrasound for the diagnosis of cardiogenic dyspnea:a meta-analysis

作　　者：蒋均仕 崔换弟 赵小鹏 张丽 杨梅[2] 周祖邦[2] Jiang Junshi;Cui Huandi;Zhao Xiaopeng;Zhang Li;Yang Mei;Zhou Zubang(Affiliated Hospital of Gansu University of Chinese Medicine,730000 Gansu,China;不详)

机构地区：[1]甘肃中医药大学附属医院,兰州730000 [2]甘肃省人民医院,兰州730000

出　　处：《中国循证心血管医学杂志》2023年第10期1166-1171,共6页Chinese Journal of Evidence-Based Cardiovascular Medicine

基　　金：甘肃省自然科学基金项目(21JR7RA599)。

摘　　要：目的通过Meta分析探讨肺脏超声检查对心源性呼吸困难的诊断价值。方法检索PubMed、Web of science、EMbase、中国生物医学文献数据库、中国知网和万方数据库,检索时间为建库至2022年4月5日,共检索文献3938篇。采用QUADAS-2对纳入文献质量进行评价并提取数据,运用I2和Cochran-Q检验行异质性检验,采用Meta-Disc 1.4软件进行数据分析。结果共纳入18篇文献。采用随机效应模型进行Meta分析,敏感度合并值为0.83(95%CI:0.81~0.85),特异度合并值为0.85(95%CI:0.83~0.86),阳性似然比合并值为5.19(95%CI:3.3~8.18),阴性似然比合并值为0.20(95%CI:0.13~0.29),诊断比值比合并值为32.51(95%CI:17.21~61.41),SROC下曲线面积合并值为0.9181。结论肺脏超声诊断心源性呼吸困难的价值及准确性较高,可成为一种新的诊断工具,但需更大样本、更科学合理的前瞻性研究予以验证。Objective To evaluate the diagnostic value of Pulmonary ultrasonography for cardiogenic dyspnea by Meta-analysis.Methods We searched PubMed,Web of Science,Embase,CBM,CNKI and WanFang Database from the database construction to April 52022,and 3938 articles were retrieved.The quality assessment of diagnostic accuracy studies(QUADAS-2)was used to evaluate the risk of bias of the included literature,then extract the data.Heterogeneity was assessed by I2 and Cochran-Q tests,and Meta-DISC 1.4 software was used to analyze data.Results A total of 18 literatures and 3558 cases were included.A random effect model was adopted for meta-analysis.The pooled sensitivity was 0.83(95%CI:0.81~0.85),the pooled specificity was 0.85(95%CI:0.83~0.86),the PLR was 5.19(95%CI:3.3~8.18),the NLR was 0.20(95%CI:0.13~0.29),the DOR was 32.51(95%CI:17.21~61.41),and the area under SROC was 0.9181.Conclusion Lung ultrasound has high accuracy and great value for the diagnosis of cardiogenic dyspnea,which can be used as a new method for diagnosing acute heart failure.However,it still needs to be verified by more scientific and reasonable prospective trials with larger samples.

关 键 词：超声检查 心力衰竭 呼吸困难 META分析 

分 类 号：R541.4[医药卫生—心血管疾病]