高血压合并高尿酸血症患者发生情况及Logistic回归分析  

A Logistic regression analysis in patients with hypertension complicated by hyperuricemia

作　　者：晁艳艳 宋晓园 王月然 孙莹莹[1] Chao Yanyan*;Song Xiaoyuan;Wang Yueran;Sun Yingying(Central Hospital of Handan City,Hebei Province,Handan 056008,China;不详)

机构地区：[1]河北省邯郸市中心医院,邯郸056008

出　　处：《中国循证心血管医学杂志》2023年第10期1253-1255,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的探讨高血压合并高尿酸血症患者发生情况及Logistic回归分析。方法选择2020年1月至2022年1月于邯郸市中心医院就诊的高血压患者236例,根据高尿酸血症发生情况分为高尿酸血症组(n=52)和对照组(n=184),收集两组患者的临床资料,分析高血压患者发生高尿酸血症的危险因素。结果236例高血压患者中52例(22.03%)发生高尿酸血症,其中男性31例(59.62%),女性21例(40.38%);单因素分析显示,两组患者在性别、吸烟、糖尿病、收缩压(SBP)、舒张压(DBP)、总胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)比较,差异无统计学意义(P>0.05);两组的年龄、文化程度、肥胖、饮酒、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)比较,差异有统计学意义(P<0.05);多因素非条件Logistic分析显示,年龄、文化程度、肥胖、饮酒、TG、HDL-C均是高血压患者发生高尿酸血症的独立危险因素(P<0.05)。结论年龄、文化程度、肥胖、饮酒、TG、HDL-C均是高血压患者发生高尿酸血症的独立危险因素,临床应针对上述危险因素进行积极干预。Objective To discuss the Logistic regression analysis in patients with hypertension complicated by hyperuricemia.Methods The patients with hypertension(n=236)were chosen from Central Hospital of Handan City from Jan.2020 to Jan.2022,and divided,according hyperuricemia occurrence,into hyperuricemia group(n=52)and control group(n=184).The clinical materials were collected and risk factors for hyperuricemia occurrence were analyzed in 2 groups.Results Among 236 hypertensive patients,there were 52 cases(22.03%)complicated by hyperuricemia,including 31 male cases(59.62%)and 21 female cases(40.38%).The results of single-factor analysis showed that the differences in gender,smoking,diabetes,systolic blood pressure(SBP),diastolic blood pressure(DBP),total cholesterol(TC)and low-density lipoprotein-cholesterol(LDL-C)had no statistical significance(P>0.05),and age,education background,obesity,drinking,triglyceride(TG)and high-density lipoprotein-cholesterol(HDL-C)had statistical significance(P<0.05)between 2 groups.The results of multi-factor non-conditional Logistic regression analysis showed that age,education background,obesity,drinking,TG and HDL-C were independent risk factors for hyperuricemia occurrence(P<0.05).Conclusion Age,education background,obesity,drinking,TG and HDL-C are independent risk factors for hyperuricemia occurrence in hypertensive patients,which should be intervened actively in clinical practice.

关 键 词：高血压 高尿酸血症 危险因素 

分 类 号：R544.1[医药卫生—心血管疾病]