水飞蓟宾胶囊保肝作用的药学研究进展  

Pharmaceutical Progress on Hepatoprotective Effects of Silibinin Capsules

作　　者：郭思瑞 邝咏梅[1] 何笑荣[1] 徐文峰[1] GUO Sirui;KUANG Yongmei;HE Xiaorong;XU Wenfeng(Dept.of Pharmacy,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Science,Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application(Beijing Hospital),Beijing 100730,China)

机构地区：[1]北京医院药学部,国家老年医学中心,中国医学科学院老年医学研究院,北京市药物临床风险与个体化应用评价重点实验室(北京医院),北京100730

出　　处：《中国医院用药评价与分析》2024年第1期116-118,123,共4页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：国家自然科学基金资助项目(No.81803715);中央高水平医院临床科研业务费资助项目(No.BJ-2021-211)。

摘　　要：水飞蓟宾胶囊是一种从水飞蓟素中提取主要成分水飞蓟宾制成的保肝药物。本文就近年来国内外关于水飞蓟宾胶囊的药学特性和药品质量研究进行综述,主要从药品的药理作用机制、临床应用、药物动力学、安全性及质量标准等多个维度对水飞蓟宾胶囊进行药学部分的讨论,为临床合理用药提供参考。Silibinin capsules are a kind of hepatoprotective drugs made from silymarin,the main ingredient in silybin.This paper reviews the pharmacological characteristics and quality of Silibinin capsules at home and abroad in recent years,and mainly discusses from the dimensions of pharmacological mechanism,clinical application,pharmacokinetics,safety and quality standards,so as to provide references for the rational use of Silibinin capsules in clinic.

关 键 词：水飞蓟宾胶囊 药理作用机制 保肝作用 质量标准 

分 类 号：R975[医药卫生—药品]