79例新型冠状病毒感染者消化道症状及其生化特征分析  

Analysis of Digestive Tract Symptoms and Biochemical Characteristics of 79 Patients Infected with Corona Virus Disease 2019

作　　者：冯尚智 陈少文 刘爱军 舒晴[2] FENG Shangzhi;CHEN Shaowen;LIU Aijun;SHU Qing(Shenzhen Dapeng New District Kuichong People's Hospital,Guangdong Shenzhen 518119;Shenzhen Second People’s Hospital,The First Affiliated Hospital of Shenzhen University,Guangdong Shenzhen 518035)

机构地区：[1]深圳市大鹏新区葵涌人民医院,广东深圳518119 [2]深圳市第二人民医院深圳大学第一附属医院,广东深圳518035

出　　处：《深圳中西医结合杂志》2023年第21期1-4,共4页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：深圳市高水平医院建设项目(深圳市第二人民医院临床研究项目)(2023yjlcyj026)。

摘　　要：目的:分析新型冠状病毒感染(COVID-19)老年组与非老年组患者的消化道症状及实验室指标特征。方法:回顾性选取2022年12月至2023年1月深圳市大鹏新区葵涌人民医院收治的79例轻型及普通型COVID-19患者作为研究对象,根据年龄分为老年组(≥60岁,35例)和非老年组(<60岁,44例),比较两组患者消化道症状及实验室指标。结果:两组患者食欲下降症状比较,差异具有统计学意义(P<0.05);两组患者腹胀恶心、腹痛、腹泻症状比较,差异无统计学意义(P>0.05)。两组患者谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素、间接胆红素、直接胆红素等生化指标比较,差异无统计学意义(P>0.05)。两组患者C反应蛋白(CRP)及乳酸脱氢酶(LDH)水平进行比较发现,其差异无统计学意义(P>0.05)。而在两组患者的肌酐水平比较中,老年组患者的肌酐水平高于非老年组,且差异具有统计学意义(P<0.05),但均值仍在正常范围。老年组粪便潜血阳性发生率为14.28%(5/35),非老年组发生率为18.18%(8/44),差异无统计学意义(P>0.05)。老年组患者血清白蛋白水平显著低于非老年组,差异具有统计学意义(P<0.05)。结论:在轻型及普通型COVID-19患者中,老年组与非老年组感染、生化等指标差异性不明显,但老年组出现消化道症状概率更高,血清白蛋白含量显著下降。老年组中食欲下降等消化道症状的出现,可能是该组患者出现血清白蛋白下降的重要原因之一。Objective To analyze the digestive tract symptoms and laboratory indexes of elderly and non-elderly patients with corona virus disease 2019(COVID-19).Methods Seventy-nine patients with mild and common COVID-19 admitted to Shenzhen Dapeng New District Kuichong People's Hospital from December 2022 to January 2023 were selected retrospectively.According to their age,they were divided into elderly group( ≥ 60 years old,35 cases) and non-elderly group(< 60 years old,44 cases),and the digestive tract symptoms and laboratory indexes of the two groups were compared.Results The difference in symptoms of decreased appetite between the two groups was statistically significant(P < 0.05).There was no statistically significant difference in the symptoms of abdominal distension,nausea,abdominal pain and diarrhea between the two groups of patients(P > 0.05).There was no statistically significant difference in indicators such as alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin indirect bilirubin,and direct bilirubin between the two groups of patients(P > 0.05).There was no statistically significant difference in the levels of C-reactive protein(CRP) and lactate dehydrogenase(LDH) between the two groups(P > 0.05).The comparison of creatinine in the elderly group showed that higher than than of the non-elderly group,and the difference was statistically significant(P < 0.05),but the average is still within the normal range.The incidence of fecal occult blood positivity in the elderly group was 14.28%(5/35),while the incidence in the non-elderly group was 18.18%(8/44),with no statistically significant difference(P > 0.05).The serum albumin level in the elderly group was significantly lower than that in the non-elderly group,and the difference was statistically significant(P < 0.05).Conclusion In patients with mild and common COVID-19,there is no obvious difference in infection,biochemistry and other indicators between the elderly group and the non-elderly group,but the elderly group has a higher probabi

关 键 词：新型冠状病毒感染 消化道症状 血清白蛋白 老年人 

分 类 号：R563.1[医药卫生—呼吸系统]