Gene X-pert MTB/RIF检测对肺结核病的诊断价值研究  

Diagnostic Value Study on Gene X-Pert MTB/RIF for Tuberculosis

作　　者：陈水平[1] CHEN Shuiping(Infection Department,Zhangjiagang City the First People's Hospital,Zhangjiagang,Jiangsu 215600)

机构地区：[1]张家港市第一人民医院感染科,江苏张家港215600

出　　处：《智慧健康》2023年第28期87-90,共4页Smart Healthcare

摘　　要：目的 研究分析肺结核病应用Gene X-pert MTB/RIF检测的诊断价值。方法 选取2022年3—10月在本院就诊的疑似肺结核病患者164例为研究对象,所有患者均给予结核分枝杆菌培养检查、痰涂片抗酸染色法诊断、Gene X-pert MTB/RIF检测,以结核分枝杆菌培养检查结果为金标准,比较痰涂片抗酸染色法诊断与Gene X-pert MTB/RIF检测的阳性率以及诊断准确性、灵敏度、特异度。结果 痰涂片抗酸染色法诊断阳性率为21.34%(35/164),Gene X-pert MTB/RIF检测阳性率为35.98%(59/164),Gene X-pert MTB/RIF检测明显高于痰涂片抗酸染色法诊断(P<0.05)。痰涂片抗酸染色法诊断的准确性为85.37%,灵敏度为59.65%,Gene X-pert MTB/RIF检测的准确性为95.12%,灵敏度为94.74%,Gene X-pert MTB/RIF检测明显高于痰涂片抗酸染色法诊断(P<0.05)。结论 在肺结核病诊断中,Gene X-pert MTB/RIF检测的阳性率更高,同时诊断准确率与灵敏度也更高,为肺结核病的诊断与治疗提供了可靠的指导依据。Objective To study and analyze diagnostic value of Gene X-pert MTB/RIF test for tuberculosis.Methods The paper chose 164 patients with suspected pulmonary tuberculosis in our hospital from March 2022 to October 2022 as study subjects,treated with Mycobacterium tuberculosis culture test,sputum acid fast staining diagnosis and Gene X-pert MTB/RIF test.Positive rate,diagnostic accuracy,sensitivity and specificity was compared between diagnosis of sputum smear acid fast staining and Gene X-pert MTB/RIF detection with gold standard results of Mycobacterium tuberculosis culture test.Results Positive rate of sputum smear acid fast staining was 21.34%(35/164),and positive rate of Gene X-pert MTB/RIF detection was 35.98%(59/164).Gene X-pert MTB/RIF detection had significantly higher effect than sputum smear acid fast staining diagnosis(P<0.05).Accuracy and sensitivity of sputum smear acid fast staining method was 85.37%and 59.65%respectively,that of Gene X-pert MTB/RIF detection was 95.12%and 94.74%respectively.Gene X-pert MTB/RIF detection had significantly higher effect than sputum smear acid fast staining method for diagnosis(P<0.05).Conclusion Gene X-pert MTB/RIF detection has a higher positive rate and higher diagnostic accuracy and sensitivity in diagnosis of tuberculosis,can provide reliable guidance for diagnosis and treatment of tuberculosis.

关 键 词：肺结核病 结核分枝杆菌培养 GeneX-pert MTB/RIF检测 诊断价值 

分 类 号：R521[医药卫生—内科学]