代谢组学在玫瑰痤疮研究中的应用进展  

Metabolomics in rosacea

作　　者：潘婼芯 顾多多 张悦[1] 李敏[1] 陶梦 许阳[1] Pan Ruoxin;Gu Duoduo;Zhang Yue;Li Min;Tao Meng;Xu Yang(Department of Dermatology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院皮肤科,南京210029

出　　处：《中华皮肤科杂志》2024年第2期178-181,共4页Chinese Journal of Dermatology

摘　　要：玫瑰痤疮是一种常见的慢性炎症性皮肤病,发病机制尚未完全阐明。代谢组学已广泛应用于生命科学领域,为探究疾病发病机制和生物标志物提供了有力依据。近年来,研究者以皮脂、泪液和唾液以及血清为样本,将代谢组学应用于玫瑰痤疮相关领域。本文综述新近代谢组学方法以及代谢组学在玫瑰痤疮研究中的应用进展。Rosacea is a common chronic inflammatory skin disease whose exact pathogenesis has not been fully elucidated.Metabolomics has been widely used in the field of life science to provide strong evidence for exploring the pathogenesis and biomarkers of diseases.In recent years,researchers have applied metabolomics to rosacea-related fields using sebum,tear,saliva,and serum samples.This review summarizes research progress on current metabolomics methods and the application of metabolomics in rosacea.

关 键 词：红斑痤疮 代谢组学 皮脂 脂肪酸类 生物标志物 

分 类 号：R758.734[医药卫生—皮肤病学与性病学]