Study of Quality Standards of Xiao’er Qingre Enema Preparation in Hospitals  

作　　者：Ruizhong Wang Yurong Zhang Junjun Mao Shaoli Liang Yan Wu Lin Chen 

机构地区：[1]Department of Pharmacy,The First Affiliated Hospital of Xi’an Medical University,Xi’an 710077,Shaanxi Province,China

出　　处：《Journal of Clinical and Nursing Research》2024年第1期125-132,共8页临床护理研究（英文）

基　　金：Xi’an Science and Technology Plan Project(Project number:23YXYJ0163);Education and Teaching Reform Research Project of Xi,an Medical University in(2023)(Project number:S202311840061);First Affiliated Hospital of Xi’an Medical University of China(Fund number:XYYFY-2023-01).

摘　　要：Objective:To establish the quality standards for the preparation of Xiao’er Qingre enema in hospitals.Method:Thin-layer chromatography(TLC)was used to identify Radix Isatidis and Glycyrrhizae in the prescription.The content of(R,S)-Goitrin was determined by high-performance liquid chromatography(HPLC).Results:In TLC identification,there was no interference between the negative controls of Radix Isatidis and glycyrrhizae,and the spots were well-separated.The HPLC results of(R,S)-Goitrin showed a good linear relationship between the peak area and concentration within the range of 0.476-95.2μg·mL-1(r=0.9999).Conclusion:The TLC and HPLC methods established in this experiment are simple,reproducible,and specific,making them suitable for the quality control Xiao’er Qingre enema preparation in hospitals.

关 键 词：Xiao’er Qingre enema (R S)-Goitrin TLC HPLC Content determination 

分 类 号：R28[医药卫生—中药学]