3,4-二氯苯基硫脲的连续化合成  

Continuous synthesis of 3,4-dichlorophenyl thiourea

作　　者：陈晓栋 彭丽君 李寒梅 唐智勇 周海斌 周贤宝 CHEN Xiaodong;PENG Lijun;LI Hanmei;TANG Zhiyong;ZHOU Haibin;ZHOU Xianbao(Zhejiang Dibang Chemical Company Limited,Shaoxing 312369,China)

机构地区：[1]浙江迪邦化工有限公司,浙江绍兴312369

出　　处：《染整技术》2024年第1期16-20,共5页Textile Dyeing and Finishing Journal

摘　　要：采用连续进料方式合成3,4-二氯苯基硫脲。考察物料投料物质的量比、体系酸值、反应温度、反应停留时间及分散剂等参数对反应的影响。较优工艺参数为:硫氰酸铵与3,4-二氯苯胺投料物质的量比1.36,酸值7%,反应温度96℃,反应时间15h,此时产品纯度可达98.5%,收率达95.93%。3,4-二氯苯基硫脲的连续化合成相比于传统间歇反应,产品纯度及收率更加稳定。3,4-dichlorophenyl thiourea was synthesized by continuous feeding.The effects of mole ratio,acid val-ue,reaction temperature,residence time and dispersant on the reaction were investigated.The optimum technological pa-rameters are as follows:the molar ratio of ammonium thiocyanate to 3,4-dichloroaniline 1.36,acid value 7%,reaction tem-perature 96℃,reaction time 15 h.Under these conditions,the purity of product is 98.5%,and the yield is 95.93%.The continuous synthesis of 3,4-dichlorophenyl thiourea is more stable in purity and yield than the traditional batch reaction.

关 键 词：染料中间体 3 4-二氯苯胺 3 4-二氯苯基硫脲 连续化 

分 类 号：TS193.2[轻工技术与工程—纺织化学与染整工程]