Gastrointestinal manifestations of critical ill heatstroke patients and their associations with outcomes:A multicentre,retrospective,observational study  

作　　者：Yu-Cong Wang Xin-Yang Jin Zheng Lei Xiao-Jiao Liu Yu Liu Bang-Guo Zhang Jian Gong Lie-Tao Wang Lv-Yuan Shi Ding-Yuan Wan Xin Fu Lu-Ping Wang Ai-Jia Ma Yi-Song Cheng Jing Yang Min He Xiao-Dong Jin Yan Kang Bo Wang Zhong-Wei Zhang Qin Wu 

机构地区：[1]Department of Critical Care Medicine,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [2]School of Pharmacy,Macao University of Science and Technology,Macao 999078,China [3]Department of Critical Care Medicine,The First People's Hospital of Ziyang City,Ziyang 641399,Sichuan Province,China [4]Department of Critical Care Medicine,The First People's Hospital of Guanghan City,Chengdu 618399,Sichuan Province,China [5]Department of Critical Care Medicine,Lezhi County Traditional Chinese Medicine Hospital,Chengdu 641599,Sichuan Province,China [6]Department of Critical Care Medicine,Chengdu Qingbaijiang District People's Hospital,Chengdu 610399,Sichuan Province,China [7]Department of Critical Care Medicine,Ziyang People's Hospital,Chengdu 641399,Sichuan Province,China

出　　处：《World Journal of Gastroenterology》2024年第4期346-366,共21页世界胃肠病学杂志（英文版）

基　　金：Supported by National Key R&D Program of China,No.2022YFC2504500;1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYGD23012.

摘　　要：BACKGROUND Extreme heat exposure is a growing health problem,and the effects of heat on the gastrointestinal(GI)tract is unknown.This study aimed to assess the incidence of GI symptoms associated with heatstroke and its impact on outcomes.AIM To assess the incidence of GI symptoms associated with heatstroke and its impact on outcomes.METHODS Patients admitted to the intensive care unit(ICU)due to heatstroke were included from 83 centres.Patient history,laboratory results,and clinically relevant outcomes were recorded at ICU admission and daily until up to day 15,ICU discharge,or death.GI symptoms,including nausea/vomiting,diarrhoea,flatulence,and bloody stools,were recorded.The characteristics of patients with heatstroke concomitant with GI symptoms were described.Multivariable regression analyses were performed to determine significant predictors of GI symptoms.RESULTS A total of 713 patients were included in the final analysis,of whom 132(18.5%)patients had at least one GI symptom during their ICU stay,while 26(3.6%)suffered from more than one symptom.Patients with GI symptoms had a significantly higher ICU stay compared with those without.The mortality of patients who had two or more GI symptoms simultaneously was significantly higher than that in those with one GI symptom.Multivariable logistic regression analysis revealed that older patients with a lower GCS score on admission were more likely to experience GI symptoms.CONCLUSION The GI manifestations of heatstroke are common and appear to impact clinically relevant hospitalization outcomes.

关 键 词：Extreme heat FLATULENCE Sunstroke Intensive care units DIARRHEA 

分 类 号：R563.1[医药卫生—呼吸系统]