阴式与腹腔镜子宫肌瘤剔除术对子宫肌瘤患者雌激素受体、性激素及性生活质量的影响  

Effects of Vaginal Myomectomyand Laparoscopic Myomectomy on Estrogen Receptor,Sex Hormone and Quality of Sexual Life in Patients with Uterine Fibroid

作　　者：曹蒙 常璐 郝玉娟 唐志会 Cao Meng;Chang Lu;Hao Yujuan;Tang Zhihui(Obstetrics and Gynecology Department,Xuchang Central Hospital,Xuchang,461000,Henan)

机构地区：[1]许昌市中心医院妇产科,河南许昌461000

出　　处：《哈尔滨医药》2023年第6期20-22,共3页Harbin Medical Journal

摘　　要：目的 观察阴式子宫肌瘤剔除术(VM)与腹腔镜子宫肌瘤剔除术(LM)对子宫肌瘤(UF)患者雌激素受体、性激素及性生活质量的影响。方法 以100例UF患者为研究对象,依照随机化分组法将其分为LM组和VM组各50例,分别使用LM和VM进行治疗。比较两组围术期基本情况(手术时间、出血量、肛门首次排气时间),对比术前、术后1周两组患者雌激素受体(ER)、性激素[促卵泡生成激素(FSH)、促黄体生成激素(LH)、雌二醇(E2)]变化情况,统计术后1周两组术后并发症发生率,观察术前、术后1个月两组患者性生活质量(性生活质量量表)。结果 VM组手术时间、出血量、肛门首次排气时间均低于LM组(P<0.05)。术后1周,两组FSH、LH水平较术前均有升高(P<0.05),ER阳性率、E2水平较术前均有降低(P<0.05),但两组间比较差异无统计学意义(P>0.05);且VM组术后并发症发生率低于LM组(P<0.05)。术后1个月,两组患者性生活质量量表评分较术前均有升高(P<0.05),且VM组高于同期LM组(P<0.05)。结论 VM与LM均能有效治疗UF,能有效改善患者雌激素受体、性激素水平。而与LM相比,VM手术时间更短、术后出血量、术后并发症更少,更有利于提高患者性生活质量。Objective To observe the effects of vaginal myomectomy(VM)and laparoscopic myomectomy(LM)on estrogen receptor,sex hormone and sex life quality in patients with uterine fibroids(UF).Methods A total of 100 UF patients were selected as research objects and divided into LM group and VM group according to block randomization,with 50 cases in each group.The LM group was treated with LM and the VM group was treated with VM.The basic information of the two groups during perioperative period(operation time,blood loss,first anal exhaust time)was compared,and the changes of ER,sex hormones(FSH,LH,E2)before and 1 week after surgery were compared between the two groups.The incidence of postoperative complications in the two groups was counted 1 week after surgery,and the quality of sexual life(sexual life quality scale)was observed in the two groups before surgery and 1 month after surgery.Results The operation time,blood loss and first anal exhaust time in VM group were lower than those in LM group(P<0.05).One week after surgery,the levels of FSH and LH in both groups were increased compared with those before surgery(P<0.05),and the positive rate of ER and the level of E2 were decreased compared with those before surgery(P<0.05).There was no significant difference between the two groups(P>0.05).The incidence of postoperative complications in VM group was lower than that in LM group(P<0.05).One month after surgery,the sex life quality scale scores in both groups were higher than those before surgery(P<0.05),and the VM group was higher than the LM group at the same period(P<0.05).Conclusions Both VM and LM can effectively treat UF and improve the levels of estrogen receptor and sex hormone in patients.Compared with LM,VM has shorter operation time,less postoperative blood loss and postoperative complications,which is more conducive to improving the quality of sexual life of patients.

关 键 词：子宫肌瘤 阴式子宫肌瘤剔除术 腹腔镜子宫肌瘤剔除术 雌激素受体 性激素 性生活质量 

分 类 号：R713.4[医药卫生—妇产科学]