高电压背根神经节脉冲射频在亚急性带状疱疹神经痛患者的临床效果观察  

The clinical effect observation on high-voltage pulsed radiofrequency of dorsal root ganglion in patients with subacute herpes zoster neuralgia

作　　者：孙晨力 郝丹丹 李修良[1] 张杰[1] 李丽[1] Sun Chenli;Hao Dandan;Li Xiuliang;Zhang Jie;Li Li(Department of Anesthesiology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院麻醉科,100050

出　　处：《北京医学》2023年第11期949-952,共4页Beijing Medical Journal

基　　金：国家自然科学基金(82271307);首都医科大学附属北京友谊医院博士后科研启动基金(yybsh2021009)。

摘　　要：目的探讨高电压背根神经节(dorsal root ganglion,DRG)脉冲射频(pulsed radiofrequency,PRF)治疗亚急性带状疱疹神经痛(herpes zoster neuralgia,HZN)的临床疗效及安全性。方法选取2021年2月至2022年5月首都医科大学附属北京友谊医院麻醉科疼痛门诊接受高电压DRG-PRF治疗的亚急性HZN患者38例,收集并比较患者术前和术后不同时点的疼痛数字等级评分量表(numerical rating scale,NRS)得分、术后6个月Likert满意度评分和术后并发症。结果38例患者中男13例、女25例;年龄46~85岁,平均(66.1±9.4)岁,BMI(23.96±3.63)kg/m2;左侧患病16例、右侧患病22例。PRF平均输出电压(93.55±3.84)V。术前、术后第1天、术后1周、术后1个月、术后3个月和术后6个月的NRS评分分别为7.00(5.00,7.00)分、1.00(1.00,4.00)分、2.50(1.00,4.25)分、2.00(0.00,4.25)分、1.00(0.00,4.00)分和1.00(1.00,3.25)分;术后各时间点的NRS评分较术前均减少,差异有统计学意义(P<0.05)。术后6个月Likert满意度评分为(4.26±0.89)分,29例对疗效满意(4分)或非常满意(5分)。所有患者均未出现神经损伤、感染等严重并发症。结论高电压DRG-PRF治疗亚急性HZN患者有效、安全,值得在临床推广应用。Objective To explore the clinical effect and safety of high-voltage pulsed radiofrequency(PRF)on dorsal root ganglion(DRG)in the treatment of subacute herpes zoster neuralgia(HZN).Methods Thirty-eight subacute HZN patients admitted to the pain clinic of the Department of Anesthesiology,Beijing Friendship Hospital Affiliated to Capital Medical University from February 2021 to May 2022 who received high-voltage DRG-PRF were selected.The numerical rating scale(NRS)scores at the time before operation and different time points after operation,the Likert satisfaction scores at six months after operation and postoperative complications of the patients were collected and analyzed.Results Among the 38 patients,there were 13 males and 25 females,the average age was(66.1±9.4)years,ranging from 46 to 85 years,the average BMI was(23.96±3.63)kg/m~2.The left side was affected in 16 cases,while the right side was involved in 22 cases.The average output voltage of PRF was(93.55±3.84)V.The NRS score were 7.00(5.00,7.00)score、1.00(1.00,4.00)score,2.50(1.00,4.25)score,2.00(0.00,4.25)score,1.00(0.00,4.00)score and 1.00(1.00,3.25)score before operation,one day after operation,one week after operation,one month after operation,three months after operation and six months after operation,respectively.The NRS score at each time point after operation was lower than that before operation,and the differences were statistically significant(all P<0.05).Likert satisfaction score at six months after operation was(4.26±0.89)score,and 29 cases were satisfied(4 points)or very satisfied(5 points)with the clinical effect.No serious complications such as nerve injury or infection occurred in all the patients.Conclusions High voltage DRG-PRF is effective and safe in the treatment of subacute HZN patients,which is worthy of clinical application.

关 键 词：带状疱疹神经痛 脉冲射频 背根神经节 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]