2013—2021年四川省艾滋病合并梅毒感染孕产妇流行病学特征及干预服务情况分析  

Epidemiological characteristics and intervention services of pregnant women infected with AIDS and syphilis in Sichuan Province

作　　者：岳岑 张刚 刘伟信 张燕 赵梓伶 张莉莉 杨茂玲 刘俐 王刚 YUE Cen;ZHANG Gang;LIU Weixin;ZHANG Yan;ZHAO Ziling;ZHANG Lili;YANG Maoling;LIU li;WANG Gang(Gynecology and obstetrics,Sichuan Provincial Maternity and Child Health Care Hospital,Sichuan Provincial Women’s and Children’s Hospital,The Affiliated Women’s and Children’s Hospital of Chengdu Medical College,Chengdu 610045,Sichuan Province,China)

机构地区：[1]四川省妇幼保健院/四川省妇女儿童医院/成都医学院附属妇女儿童医院妇产科,成都610045

出　　处：《预防医学情报杂志》2024年第1期11-17,共7页Journal of Preventive Medicine Information

摘　　要：目的分析2013—2021年四川省艾滋病合并梅毒感染孕产妇流行特征及干预服务情况,为制定工作策略提供科学依据。方法收集2013—2021年四川省艾滋病、梅毒感染孕产妇及所生儿童资料,对艾滋病合并梅毒感染孕产妇的基本情况采用描述性流行病学方法进行分析,对分娩的艾滋病合并梅毒感染产妇及所生儿童干预服务情况的差异采用χ^(2)_(趋势)检验进行分析。以P<0.05为差异有统计学意义。结果2013—2021年四川省共报告艾滋病合并梅毒感染470例,孕产妇平均年龄为(29.80±5.93)岁,学历为小学及以下占74.25%,妊娠结局为分娩占73.83%。艾滋病合并梅毒感染产妇孕早期抗艾滋病病毒用药率由2013年8.33%升高至2021年96.05%(χ^(2)_(趋势)=168.635,P<0.001),孕早期梅毒治疗率由2013年0%升高至2021年31.58%(χ^(2)_(趋势)=30.113,P<0.001)。艾滋病合并梅毒感染产妇所生存活儿童抗艾滋病病毒用药率由2013年83.33%升高至2021年100.00%(χ^(2)_(趋势)=18.341,P<0.001),预防性梅毒治疗率由2013年50.00%升高至2021年97.37%(χ^(2)_(趋势)=15.316,P<0.001)。结论四川省预防母婴传播相关干预服务指标明显改善,但梅毒治疗及时性和孕产期保健服务次数需加强。应提高孕产期保健服务质量,强化梅毒感染孕产妇治疗工作。Objective To analyze the epidemiological characteristics and intervention services of pregnant women infected with HIV and syphilis in Sichuan Province from 2013 to 2021 in order to provide a scientific basis for formulating work strategies.Methods Data of pregnant women with AIDS or syphilis and their children in Sichuan Province from 2013 to 2021 were collected.Descriptive statistics were performed to analyze the basic information of pregnant women with AIDS and syphilis,and trend chi-square was used to analyze the intervention services of pregnant women with AIDS and syphilis and their children with the test levelα=0.05.Results The average 11 age of 470 HIV-infected pregnant women with syphilis was 29.80±5.93 years old,the education level of primary school or below accounted for 74.25%,and the pregnancy outcome was childbirth accounted for 73.83%.The rate of taking anti-HIV drugs in women with HIV and syphilis in early pregnancy increased from 8.33%in 2013 to 96.05%in 2021(χ^(2)=168.635,P<0.001),and the rate of syphilis treatment in early pregnancy increased from 0%in 2013 to 31.58%in 2021(χ^(2)=30.113,P<0.001).The rate of anti-HIV drugs and preventive syphilis treatment increased from 83.33%in 2013 to 100.00%in 2021(χ^(2)=18.341,P<0.001),and the rate of preventive syphilis treatment increased from 50.00%in 2013 to 97.37%in 2021(χ^(2)=15.316,P<0.001).Conclusions The indicators of intervention services for prevention of mother-to-child transmission have been significantly improved in Sichuan province,but the timeliness of syphilis treatment and the frequency of maternal care services need to be strengthened.It is necessary to improve the quality of maternal health care services and strengthen the treatment of pregnant women with syphilis infection.

关 键 词：艾滋病 梅毒 合并感染 孕产妇 流行病学 

分 类 号：R512.91[医药卫生—内科学]