基于重振雄阳法探讨天雄散治疗特发性少弱精症并见昼夜节律紊乱  

Investigate the Application of Tianxiong San in the Treatment of Idiopathic Oligoasthenospermia with Circadian Rhythm Disorder Based on Revitalizing Xiongyang Method

作　　者：冯恩敏 杨扬 谢雨宏 刘恒杰 黄鑫 王能 周青[1] FENG Enmin;YANG Yang;XIE Yuhong;LIU Hengjie;HUANG Xin;WANG Neng;ZHOU Qing(The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410007,China)

机构地区：[1]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《云南中医药大学学报》2023年第6期18-23,共6页Journal of Yunnan University of Chinese Medicine

基　　金：湖南省性与生殖健康中医临床医学研究中心(2020SK4014);湖南省一类中医重点专科(中医男科)(湘中医药函[2023]4号);湖南省研究生科研创新项目(QL20230200)。

摘　　要：少弱精症有过半原因不能明确,而昼夜节律紊乱可能是其中一大原因。基于中医理论,探讨特发性少弱精子并见昼夜节律紊乱的病机和治法特点。认为其基本病机在于“肾主生殖”的功能失职,阴阳失于调摄,具体为阳不入阴,初阳不生,在精液病机表现为“精气清冷”。从而提出“重振雄阳法”,意在调节肾之阴阳,助阳初生,重振雄风。作为重振雄阳的经典代表方,天雄散有温振肾阳,镇阴潜阳,助阳初生之功,符合特发性少弱精症并见昼夜节律紊乱的治疗要求。结合现代研究进展和方药分析,该方可能会在调节昼夜节律和改善少弱精症等方面具有一定治疗作用。因此,提出天雄散运用于特发性少弱精症并见昼夜节律紊乱的治疗,以期为中医临床治疗提供新思路。Oligoasthenospermia has more than half of the causes that cannot be identified,and circadian rhythm disturbances may be one of the major causes.Based on the theory of traditional Chinese medicine(TCM).This paper discusses the pathogenesis and treatment characteristics of idiopathic oligoasthenozoospermia with circadian rhythm disorder.It is considered that its basic pathogenesis lies in the functional dereliction of duty of"kidney dominates reproduction"and the loss of Yin and Yang in regulation,Namely,Yang does not enter Yin and the initial Yang cannot grow.In the pathogenesis of semen,it is manifested as"essence and cold".Thus,the paper proposes"revitalizae Xiongyang method",which is intended to regulate the Yin and Yang of the kidney,assist Yang growing,and revitalize male reproductive function.As a classic representative formula for revitalizing Xiongyang,Tianxiong San has the functions of warming and evoking kidney-Yang,down-regulating Yin and up-regualting Yang,and assisting Yang growing,which meets the treatment requirements of idiopathic oligoasthenospermia with circadian rhythm disorder.Combined with modern research progress and prescription analysis,this prescription may have a certain therapeutic effect in regulating circadian rhythm and improving oligoasthenospermia.Therefore,it is proposed that Tianxiong San can be used in the treatment of idiopathic oligoas-thenospermia with circadian rhythm disorder in order to provide new ideas for the clinical treatment of TCM.

关 键 词：特发性少弱精症 昼夜节律紊乱 重振雄阳法 天雄散 男性不育症 

分 类 号：R277.5[医药卫生—中医学]