显微镜下精索静脉结扎术联合中医药治疗精索静脉曲张性不育的临床观察  

Clinical Observation of Spermatic Vein Ligation under Microscope Combined with Traditional Chinese Medicine in Treatment of Varicocele Infertility

作　　者：张凯[1] 王宁宁 马楠[1] 郭绍永[1] 李虎[1] ZHANG Kai;WANG Ningning;MA Nan;GUO Shaoyong;LI Hu(Department of Urology,General Hospital of Wanbei Coal and Electricity Group,Suzhou 234000,China)

机构地区：[1]皖北煤电集团总医院/蚌埠医学院附属第三医院泌尿外科,安徽宿州234000

出　　处：《云南中医药大学学报》2023年第6期61-65,共5页Journal of Yunnan University of Chinese Medicine

基　　金：蚌埠医学院校级项目课题(2020byzd364)。

摘　　要：目的观察显微镜下精索静脉结扎术联合中医药在精索静脉曲张性不育治疗中的临床疗效。方法按照随机数字表法随机将2021年4月至2022年6月本院收治的80例精索静脉曲张性不育患者分成2组,每组各40例,观察组行显微镜下精索静脉结扎术联合中医药治疗,对照组单纯行显微镜下精索静脉结扎术治疗,比较2组术前、术后6个月精液参数(精子浓度、前向运动精子、正常形态精子、精子DNA碎片指数),以及性激素水平、配偶自然怀孕率等情况。结果术后6个月,观察组精子浓度、前向运动精子、正常形态精子、精子DNA碎片率均较前改善,且改善率观察组明显优于对照组,差异均有统计学意义(P<0.05);观察组的术后血清睾酮、卵泡刺激素、黄体生成素水平改善情况优于对照组,差异均有统计学意义(P<0.05);观察组总有效率为87.5%,明显优于对照组的75.0%,且观察组自然妊娠率高于对照组。结论显微镜下精索静脉结扎手术联合中医药治疗精索静脉曲张性不育疗效满意,精液参数改善明显,临床值得推广。Objective To observe the clinical efficacy of Spermatic vein ligation under microscope combined with traditional Chinese medicine in treatment of varicocele infertility.Method According to the random number table method,80 patients with varicocele infertility admitted to our hospital from April 2021 to June 2022,were randomly divided into two groups,each group with 40 cases,the observation group underwent microscopic spermaceleous vein ligation combined with traditional Chinese medicine,and the control group was treated with microscopic spermatic vein ligation.Semen parameters(sperm concentration,forward motile sperm,normal form sperm,sperm DNA fragmentation index),sex hormone levels and natural pregnancy rate of spouses of the two groups were compared before and 6 months after surgery.Result Six months after surgery,the sperm concentration,forward motility sperm,normal morphologic sperm and sperm DNA fragmentation rate in the observation group were all improved,and the improvement rate in the observation group was significantly better than that in the control group,the differences were statistically significant(P<0.05).The improvement of serum levels of testosterone,follicle stimulating hormone and luteinizing hormone in the observation group was better than that in the control group(P<0.05).The total effective rate of the observation group was 87.5%,which was significantly better than 75.0%of the control group,and the natural pregnancy rate of the observation group was higher than that of the control group.Conclusion The effect of Spermatic vein ligation under microscope combined with traditional Chinese medicine in the treatment of varicocele sterility is satisfactory,and the semen parameters are obviously improved.

关 键 词：精索静脉曲张 显微镜 中医药 精液参数 

分 类 号：R256.56[医药卫生—中医内科学]