黄芩质量形成影响因素的研究进展  

Research progress on influencing factors of quality formation of Scutellariae Radix

作　　者：韩志超 梁运江[2] 赛春梅 HAN Zhichao;LIANG Yunjiang;SAI Chunmei(College of Pharmacy,Jining Medical University,Rizhao 276826,China;College of Agriculture,Yanbian University,Yanji 133002,China)

机构地区：[1]济宁医学院药学院,山东日照276826 [2]延边大学农学院,吉林延吉133002

出　　处：《中草药》2024年第1期320-331,共12页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(31800282);山东省自然科学基金面上项目(ZR2023MC009)。

摘　　要：黄芩Scutellariae Radix是我国常用的大宗中药材,在建设健康中国、维护世界公共卫生安全方面具有重要作用。种质及生态环境对黄芩次生代谢产物的合成与积累具有显著影响。通过对关于黄芩质量形成与种质、气候及土壤因子的相关性的研究进行综述,并在此基础上提出,在中医药理论的指导下,充分理解黄芩栽培的特殊性,并重视多学科交叉、分子生药学、土壤酶、内生微生物、微生物组学及多组学等研究,是未来黄芩质量形成影响因素的研究重点,为指导黄芩栽培提供参考。Huangqin(Scutellariae Radix),a frequently used and mass traditional Chinese medicine,plays an important role in building healthy China and maintaining global public health security.The germplasm and ecological environment make a difference to the synthesis and accumulation of secondary metabolites of Scutellariae Radix.This paper reviewed the correlations between quality formation of Scutellariae Radix and germplasm,climatic and soil factors.It was then proposed that under the guidance of the traditional Chinese medicine theory,fully understanding the particularity of the cultivation of Scutellariae Radix,and paying attention to the multidisciplinary and interdisciplinary,molecular pharmacognostics,soil enzymes,endophytic microorganisms,microbiomics and multi-omics studies should be the future research focus of influencing factors on the quality formation of Scutellariae Radix on this basis.This paper provided a meaningful reference for the cultivation of Scutellariae Radix.

关 键 词：黄芩 质量形成 黄芩苷 黄芩素 汉黄芩苷 汉黄芩素 种质 生态环境 

分 类 号：R283[医药卫生—中药学]