近现代新安医家治疗郁证用药规律分析  

Analysis of the Patterns of Medication used in the Treatment of Depression by Modern Xin’an Physicians

作　　者：戎荣 马守亮[2] RONG Rong;MA Shouliang(Anhui University of Chinese Medicine,Anhui Hefei 230000,China;The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Anhui Hefei 230000,China)

机构地区：[1]安徽中医药大学研究生院,安徽合肥230000 [2]安徽中医药大学第一附属医院,安徽合肥230000

出　　处：《中医药临床杂志》2024年第1期98-103,共6页Clinical Journal of Traditional Chinese Medicine

基　　金：中国中医药管理局第七批全国老中医专家学术经验继承资助项目(2022);安徽省新冠病毒科研应急攻关专项公开竞争项目(2022e07020082)。

摘　　要：目的:通过对近现代新安医家的病案及处方进行收集整理及数据分析,探讨近现代新安医家治疗郁证用药特色,为临床治疗郁证进一步提供新思路。方法:通过检索,收集整理近现代新安医家有关治疗郁证的病案及处方,应用中医传承辅助平台V2.5(TCMISS V2.5)进行频数统计、关联规则及聚类分析。结果:研究共纳入154个中医方剂,涉及259味中药,排列前10为白芍、酸枣仁、淮小麦、远志、柴胡、丹参、竹茹、陈皮、绿萼梅、黄连;药性多为温、寒、平,药味以苦、辛、甘为主,多归肝、脾胃、心经。发现37条高度相关规则,频度靠前的有酸枣仁-远志、酸枣仁-淮小麦、远志-淮小麦等;聚类分析得出核心药物组合26个,新处方9首。结论:发现近现代新安医家用药配伍严谨,善于治疗郁证伴有不寐、心烦、纳差、胃脘不舒等兼症,能够为郁证的临床辨证提供一定参考依据。Objective:By collecting and analyzing the medical records and prescriptions of modern Xin’an physicians,we explore the characteristics of modern Xin’an physicians’medication for depression syndrome,and provide new ideas for the clinical treatment of depression syndrome.Methods:Through retrieval,medical records and prescriptions related to the treatment of depression syndrome by modern Xin’an physicians were collected and sorted,and frequency statistics,association rules and cluster analysis were conducted using Traditional Chinese Medicine Inheritance Assistance Platform V2.5(TCMISS V2.5).Results:A total of 154 TCM prescriptions were included in the study,involving 259 traditional Chinese medicines.The top 10 were white peony root,wild jujube kernel,Huaimai wheat,Polygala root,Bupleurum root,salvia miltiorrhiza,bamboo root,dried tangerine peel,green calyx plum,and Coptidis rhizome.Most of the medicinal properties were warming.,cold,flat,the medicinal taste is mainly bitter,pungent,and sweet,and is mostly attributed to the liver,spleen,stomach,and heart meridians.37 highly correlated rules were found,with the most frequent ones being Ziziphus jujuba kernel-Polygala,Polygala jujube-Huaimai,Polygala polygala-Huaimai,etc.Cluster analysis revealed 26 core drug combinations and 9 new prescriptions.Conclusion:It is found that modern Xin’an medical practitioners have strict compatibility of medicines and are good at treating depression syndrome accompanied by insomnia,restlessness,anorexia,epigastric discomfort and other concurrent symptoms,which can provide certain reference basis for the clinical differentiation of depression syndrome.

关 键 词：近现代 新安医学 郁证 用药规律 

分 类 号：R249.8[医药卫生—中医临床基础]