不同产地鱼腥草药材质量的综合评价  

Comprehensive evaluation of the quality of Houttuynia cordata from different producing areas

作　　者：温倪婷 杨昌贵 周涛 康传志 赵丹 王升[2] 江维克 WEN Niting;YANG Changgui;ZHOU Tao;KANG Chuanzhi;ZHAO Dan;WANG Sheng;JIANG Weike(Resource Institute for Chinese&Ethnic Materia Medica,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;National Resource Center for Chinese Materia Medica,Chinese Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]贵州中医药大学中药民族药资源研究院,贵阳550025 [2]中国中医科学院中药资源中心,北京100700

出　　处：《中国药房》2024年第4期425-429,共5页China Pharmacy

基　　金：国家中药材产业技术体系项目;贵州省高层次创新型人才项目(No.黔科合平台人才[2018]5638);贵州省教育厅高校科研平台项目(No.黔教技[2022]021号);中国中医科学院科技创新工程项目。

摘　　要：目的评价不同产地鱼腥草药材的综合质量。方法以总黄酮、浸出物、水分、总灰分、酸不溶性灰分为指标,采用熵权法对各指标客观赋权,以灰色关联度分析法计算的相对关联度(ri)为测度,综合评价鱼腥草药材的质量。结果总黄酮、总灰分、水分、酸不溶性灰分、浸出物的权重分别为0.2955、0.2273、0.1887、0.1451、0.1434,总黄酮和总灰分的权重相对较大。30批药材的ri为0.2332~0.6739,以广西壮族自治区全州县和资源县产样品的平均ri最高,分别为0.6383、0.5987,其次为广西壮族自治区灵川县(0.5561)和云南省建水县(0.4528),上述产地药材质量整体较好且稳定。结论熵权法结合灰色关联度分析法可用于综合评价鱼腥草药材的质量;广西壮族自治区全州县产的鱼腥草药材整体质量最优。OBJECTIVE To evaluate the comprehensive quality of Houttuynia cordata from different producing areas.METHODS Using total flavonoids,water-soluble extract,moisture,total ash and acid-insoluble ash as indicators,the entropy weight method was used to objectively weigh each indicator,and the relative correlation degree(ri)calculated by grey correlation method was used as a measure to comprehensively evaluate the quality of H.cordata.RESULTS The weights of total flavonoids,total ash,moisture,acid-insoluble ash,and water-soluble extract were 0.2955,0.2273,0.1887,0.1451,and 0.1434,respectively.The weights of total flavonoids and total ash were relatively large.The ri of 30 batches of H.cordata ranged from 0.2332 to 0.6739;the average ri of samples from Quanzhou County and Ziyuan County of Guangxi Zhuang Autonomous Region were the highest,which were 0.6383 and 0.5987,respectively,followed by samples from Lingchuan County of Guangxi Zhuang Autonomous Region(0.5561)and Jianshui County of Yunnan Province(0.4528).The quality of medicinal materials produced in the above producing areas was generally good and stable.CONCLUSIONS Entropy weight method combined with the grey correlation method can be used to comprehensively evaluate the quality of H.cordata.The overall quality of H.cordata produced in Quanzhou County of Guangxi Zhuang Autonomous Region is the best.

关 键 词：鱼腥草 灰色关联度分析法 熵权法 多指标 综合评价 

分 类 号：R917[医药卫生—药物分析学] R284.1[医药卫生—药学]